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4guk

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4guk| PDB=4guk | SCENE= }}
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===New crystal form structure of human NCS1===
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The entry 4guk is ON HOLD until Dec 19 2014
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==Function==
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[[http://www.uniprot.org/uniprot/NCS1_HUMAN NCS1_HUMAN]] Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity).
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Authors: Chengpeng F., Elias L.
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==About this Structure==
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[[4guk]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GUK OCA].
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Description: New crystal form structure of human NCS1
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[[Category: F., Chengpeng.]]
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[[Category: L., Elias.]]
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[[Category: Alpha]]
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[[Category: Neuronal calcium sensor]]
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[[Category: Protein binding]]

Revision as of 10:24, 25 December 2013

Template:STRUCTURE 4guk

New crystal form structure of human NCS1

Function

[NCS1_HUMAN] Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity).

About this Structure

4guk is a 4 chain structure. Full crystallographic information is available from OCA.

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OCA

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