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4emp
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4emp| PDB=4emp | SCENE= }} | {{STRUCTURE_4emp| PDB=4emp | SCENE= }} | ||
===Crystal structure of the mutant of ClpP E137A from Staphylococcus aureus=== | ===Crystal structure of the mutant of ClpP E137A from Staphylococcus aureus=== | ||
| + | {{ABSTRACT_PUBMED_23625918}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
| - | [[4emp]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4emp]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Staaw Staaw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EMP OCA]. |
| + | |||
| + | ==See Also== | ||
| + | *[[Clp Protease|Clp Protease]] | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023625918</ref><references group="xtra"/><references/> | ||
[[Category: Endopeptidase Clp]] | [[Category: Endopeptidase Clp]] | ||
| - | [[Category: | + | [[Category: Staaw]] |
[[Category: Liu, H.]] | [[Category: Liu, H.]] | ||
[[Category: Luo, C.]] | [[Category: Luo, C.]] | ||
Revision as of 10:48, 1 January 2014
Contents |
Crystal structure of the mutant of ClpP E137A from Staphylococcus aureus
Template:ABSTRACT PUBMED 23625918
Function
[CLPP_STAAW] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).
About this Structure
4emp is a 14 chain structure with sequence from Staaw. Full crystallographic information is available from OCA.
See Also
Reference
- Ye F, Zhang J, Liu H, Hilgenfeld R, Zhang R, Kong X, Li L, Lu J, Zhang X, Li D, Jiang H, Yang CG, Luo C. Helix unfolding/refolding characterizes the functional dynamics of Staphylococcus aureus Clp protease. J Biol Chem. 2013 Jun 14;288(24):17643-53. doi: 10.1074/jbc.M113.452714. Epub, 2013 Apr 26. PMID:23625918 doi:http://dx.doi.org/10.1074/jbc.M113.452714
