4c6c
From Proteopedia
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- | + | {{STRUCTURE_4c6c| PDB=4c6c | SCENE= }} | |
+ | ===Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from HEK293 cells.=== | ||
+ | {{ABSTRACT_PUBMED_24332717}} | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/PYR1_HUMAN PYR1_HUMAN]] This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase). | ||
- | + | ==About this Structure== | |
+ | [[4c6c]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C6C OCA]. | ||
- | + | ==Reference== | |
+ | <ref group="xtra">PMID:024332717</ref><references group="xtra"/><references/> | ||
+ | [[Category: Gly-Xaa carboxypeptidase]] | ||
+ | [[Category: Grande-Garcia, A.]] | ||
+ | [[Category: Lallous, N.]] | ||
+ | [[Category: Ramon-Maiques, S.]] | ||
+ | [[Category: Amidohydrolase superfamily]] | ||
+ | [[Category: De novo pyrimidine biosynthesis]] | ||
+ | [[Category: Histidinate anion]] | ||
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Metalloenzyme]] | ||
+ | [[Category: Zinc binding]] |
Revision as of 10:02, 8 January 2014
Contents |
Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from HEK293 cells.
Template:ABSTRACT PUBMED 24332717
Function
[PYR1_HUMAN] This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).
About this Structure
4c6c is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Grande-Garcia A, Lallous N, Diaz-Tejada C, Ramon-Maiques S. Structure, Functional Characterization, and Evolution of the Dihydroorotase Domain of Human CAD. Structure. 2013 Dec 10. pii: S0969-2126(13)00428-0. doi:, 10.1016/j.str.2013.10.016. PMID:24332717 doi:http://dx.doi.org/10.1016/j.str.2013.10.016