3ale

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[[Image:3ale.png|left|200px]]
 
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{{STRUCTURE_3ale| PDB=3ale | SCENE= }}
{{STRUCTURE_3ale| PDB=3ale | SCENE= }}
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===A type III polyketide synthase that produces diarylheptanoid===
===A type III polyketide synthase that produces diarylheptanoid===
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{{ABSTRACT_PUBMED_21041675}}
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{{ABSTRACT_PUBMED_021041675}}
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==Function==
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[[http://www.uniprot.org/uniprot/CUS_ORYSJ CUS_ORYSJ]] Plant-specific type III polyketide synthase (PKS) that catalyzes the one-pot formation of the C6-C7-C6 diarylheptanoid scaffold of bisdemethoxycurcumin by the condensation of two molecules of 4-coumaroyl-CoA and one molecule of malonyl-CoA.<ref>PMID:21041675</ref>
==About this Structure==
==About this Structure==
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[[3ale]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ALE OCA].
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[[3ale]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ALE OCA].
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[[Category: Oryza sativa]]
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==Reference==
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<ref group="xtra">PMID:021041675</ref><references group="xtra"/><references/>
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[[Category: Japanese rice]]
[[Category: Abe, I.]]
[[Category: Abe, I.]]
[[Category: Kato, R.]]
[[Category: Kato, R.]]

Revision as of 05:53, 22 January 2014

Template:STRUCTURE 3ale

Contents

A type III polyketide synthase that produces diarylheptanoid

Template:ABSTRACT PUBMED 21041675

Function

[CUS_ORYSJ] Plant-specific type III polyketide synthase (PKS) that catalyzes the one-pot formation of the C6-C7-C6 diarylheptanoid scaffold of bisdemethoxycurcumin by the condensation of two molecules of 4-coumaroyl-CoA and one molecule of malonyl-CoA.[1]

About this Structure

3ale is a 4 chain structure with sequence from Japanese rice. Full crystallographic information is available from OCA.

Reference

  • Morita H, Wanibuchi K, Nii H, Kato R, Sugio S, Abe I. Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativa. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19778-83. Epub 2010 Nov 1. PMID:21041675 doi:http://dx.doi.org/10.1073/pnas.1011499107
  1. ↑ Morita H, Wanibuchi K, Nii H, Kato R, Sugio S, Abe I. Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativa. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19778-83. Epub 2010 Nov 1. PMID:21041675 doi:http://dx.doi.org/10.1073/pnas.1011499107

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