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2r0k

From Proteopedia

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[[Image:2r0k.png|left|200px]]
 
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{{STRUCTURE_2r0k| PDB=2r0k | SCENE= }}
{{STRUCTURE_2r0k| PDB=2r0k | SCENE= }}
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===Protease domain of HGFA with inhibitor Fab58===
===Protease domain of HGFA with inhibitor Fab58===
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{{ABSTRACT_PUBMED_18077410}}
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{{ABSTRACT_PUBMED_18077410}}
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==Function==
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[[http://www.uniprot.org/uniprot/HGFA_HUMAN HGFA_HUMAN]] Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.
==About this Structure==
==About this Structure==
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[[2r0k]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0K OCA].
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[[2r0k]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0K OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:018077410</ref><references group="xtra"/>
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<ref group="xtra">PMID:018077410</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Eigenbrot, C.]]
[[Category: Eigenbrot, C.]]
[[Category: Shia, S.]]
[[Category: Shia, S.]]

Revision as of 08:17, 5 February 2014

Template:STRUCTURE 2r0k

Contents

Protease domain of HGFA with inhibitor Fab58

Template:ABSTRACT PUBMED 18077410

Function

[HGFA_HUMAN] Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.

About this Structure

2r0k is a 3 chain structure with sequence from [1] and Human. Full crystallographic information is available from OCA.

See Also

Reference

  • Wu Y, Eigenbrot C, Liang WC, Stawicki S, Shia S, Fan B, Ganesan R, Lipari MT, Kirchhofer D. Structural insight into distinct mechanisms of protease inhibition by antibodies. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19784-9. Epub 2007 Dec 5. PMID:18077410

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