2eiz
From Proteopedia
(Difference between revisions)
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- | [[Image:2eiz.png|left|200px]] | ||
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{{STRUCTURE_2eiz| PDB=2eiz | SCENE= }} | {{STRUCTURE_2eiz| PDB=2eiz | SCENE= }} | ||
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===Crystal structure of humanized HYHEL-10 fv mutant(HW47Y)-hen lysozyme complex=== | ===Crystal structure of humanized HYHEL-10 fv mutant(HW47Y)-hen lysozyme complex=== | ||
+ | {{ABSTRACT_PUBMED_18227432}} | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> | ||
==About this Structure== | ==About this Structure== | ||
- | [[2eiz]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[2eiz]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIZ OCA]. |
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID:018227432</ref><references group="xtra"/> | + | <ref group="xtra">PMID:018227432</ref><references group="xtra"/><references/> |
- | [[Category: | + | [[Category: Chick]] |
- | [[Category: | + | [[Category: Human]] |
[[Category: Lysozyme]] | [[Category: Lysozyme]] | ||
[[Category: Kondo, H.]] | [[Category: Kondo, H.]] |
Revision as of 14:13, 3 March 2014
Contents |
Crystal structure of humanized HYHEL-10 fv mutant(HW47Y)-hen lysozyme complex
Template:ABSTRACT PUBMED 18227432
Function
[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]
About this Structure
2eiz is a 3 chain structure with sequence from Chick and Human. Full crystallographic information is available from OCA.
See Also
Reference
- Nakanishi T, Tsumoto K, Yokota A, Kondo H, Kumagai I. Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10. Protein Sci. 2008 Feb;17(2):261-70. PMID:18227432 doi:http://dx.doi.org/17/2/261
- ↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021