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4mfv

From Proteopedia

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m (Protected "4mfv" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4mfv| PDB=4mfv | SCENE= }}
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===Crystal structure of human CTNNBL1(residues 33~563)===
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The entry 4mfv is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/CTBL1_HUMAN CTBL1_HUMAN]] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.<ref>PMID:12659813</ref> <ref>PMID:18722174</ref>
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Authors: Ahn, J.W., Kim, S., Kim, K.J.
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==About this Structure==
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[[4mfv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MFV OCA].
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Description: Crystal structure of human CTNNBL1(residues 33~563)
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Ahn, J W.]]
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[[Category: Kim, K J.]]
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[[Category: Kim, S.]]
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[[Category: Arm repeat]]
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[[Category: Gene regulation]]

Revision as of 14:00, 12 March 2014

Template:STRUCTURE 4mfv

Contents

Crystal structure of human CTNNBL1(residues 33~563)

Function

[CTBL1_HUMAN] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.[1] [2]

About this Structure

4mfv is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Jabbour L, Welter JF, Kollar J, Hering TM. Sequence, gene structure, and expression pattern of CTNNBL1, a minor-class intron-containing gene--evidence for a role in apoptosis. Genomics. 2003 Mar;81(3):292-303. PMID:12659813
  2. ↑ Conticello SG, Ganesh K, Xue K, Lu M, Rada C, Neuberger MS. Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1. Mol Cell. 2008 Aug 22;31(4):474-84. doi: 10.1016/j.molcel.2008.07.009. PMID:18722174 doi:10.1016/j.molcel.2008.07.009

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