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1qs3
From Proteopedia
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{{STRUCTURE_1qs3| PDB=1qs3 | SCENE= }} | {{STRUCTURE_1qs3| PDB=1qs3 | SCENE= }} | ||
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===NMR SOLUTION CONFORMATION OF AN ANTITOXIC ANALOG OF ALPHA-CONOTOXIN GI=== | ===NMR SOLUTION CONFORMATION OF AN ANTITOXIC ANALOG OF ALPHA-CONOTOXIN GI=== | ||
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{{ABSTRACT_PUBMED_10508392}} | {{ABSTRACT_PUBMED_10508392}} | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/CA1A_CONGE CA1A_CONGE]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. The higher affinity site for alpha-conotoxin GI is the alpha/delta site on mouse muscle-derived BC3H-1 receptor, and the other site (alpha/gamma site) on nicotinic receptors from Torpedo californica electric organ. | ||
==About this Structure== | ==About this Structure== | ||
[[1qs3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QS3 OCA]. | [[1qs3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QS3 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:010508392</ref><references group="xtra"/><references/> | ||
[[Category: Han, K H.]] | [[Category: Han, K H.]] | ||
[[Category: Mok, K H.]] | [[Category: Mok, K H.]] | ||
Revision as of 14:13, 12 March 2014
Contents |
NMR SOLUTION CONFORMATION OF AN ANTITOXIC ANALOG OF ALPHA-CONOTOXIN GI
Template:ABSTRACT PUBMED 10508392
Function
[CA1A_CONGE] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. The higher affinity site for alpha-conotoxin GI is the alpha/delta site on mouse muscle-derived BC3H-1 receptor, and the other site (alpha/gamma site) on nicotinic receptors from Torpedo californica electric organ.
About this Structure
1qs3 is a 1 chain structure. Full experimental information is available from OCA.
Reference
- Mok KH, Han KH. NMR solution conformation of an antitoxic analogue of alpha-conotoxin GI: identification of a common nicotinic acetylcholine receptor alpha 1-subunit binding surface for small ligands and alpha-conotoxins. Biochemistry. 1999 Sep 14;38(37):11895-904. PMID:10508392
