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4bme

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'''Unreleased structure'''
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{{STRUCTURE_4bme| PDB=4bme | SCENE= }}
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===Crystal structure of the N terminal domain of human Galectin 8, F19Y mutant===
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{{ABSTRACT_PUBMED_24418318}}
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The entry 4bme is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN]] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref>
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Authors: Buzamet, E., Ruiz, F.M., Menendez, M., Romero, A., Gabius, H.J., Solis, D.
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==About this Structure==
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[[4bme]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BME OCA].
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Description: Crystal structure of the N terminal domain of human Galectin 8, F19Y mutant
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==Reference==
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<ref group="xtra">PMID:024418318</ref><references group="xtra"/><references/>
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[[Category: Buzamet, E.]]
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[[Category: Gabius, H J.]]
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[[Category: Menendez, M.]]
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[[Category: Romero, A.]]
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[[Category: Ruiz, F M.]]
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[[Category: Solis, D.]]
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[[Category: Carbohydrate recognition]]
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[[Category: Sugar binding protein]]

Revision as of 08:42, 19 March 2014

Template:STRUCTURE 4bme

Contents

Crystal structure of the N terminal domain of human Galectin 8, F19Y mutant

Template:ABSTRACT PUBMED 24418318

Function

[LEG8_HUMAN] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.[1]

About this Structure

4bme is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Ruiz FM, Scholz BA, Buzamet E, Kopitz J, Andre S, Menendez M, Romero A, Solis D, Gabius HJ. Natural single amino acid polymorphism (F19Y) in human galectin-8: detection of structural alterations and increased growth-regulatory activity on tumor cells. FEBS J. 2014 Mar;281(5):1446-64. doi: 10.1111/febs.12716. Epub 2014 Feb 3. PMID:24418318 doi:http://dx.doi.org/10.1111/febs.12716
  1. ↑ Ideo H, Matsuzaka T, Nonaka T, Seko A, Yamashita K. Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans. J Biol Chem. 2011 Apr 1;286(13):11346-55. Epub 2011 Feb 2. PMID:21288902 doi:10.1074/jbc.M110.195925

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OCA

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