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4ckl
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4ckl| PDB=4ckl | SCENE= }} | {{STRUCTURE_4ckl| PDB=4ckl | SCENE= }} | ||
===Structure of 55 kDa N-terminal domain of E. coli DNA gyrase A subunit with simocyclinone D8 bound=== | ===Structure of 55 kDa N-terminal domain of E. coli DNA gyrase A subunit with simocyclinone D8 bound=== | ||
| + | {{ABSTRACT_PUBMED_24594357}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4ckl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CKL OCA]. | [[4ckl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CKL OCA]. | ||
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| + | ==See Also== | ||
| + | *[[Gyrase|Gyrase]] | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:024594357</ref><references group="xtra"/><references/> | ||
[[Category: Edwards, M J.]] | [[Category: Edwards, M J.]] | ||
[[Category: Hearnshaw, S J.]] | [[Category: Hearnshaw, S J.]] | ||
Revision as of 09:04, 19 March 2014
Contents |
Structure of 55 kDa N-terminal domain of E. coli DNA gyrase A subunit with simocyclinone D8 bound
Template:ABSTRACT PUBMED 24594357
Function
[GYRA_SHIFL] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity).
About this Structure
4ckl is a 2 chain structure. Full crystallographic information is available from OCA.
See Also
Reference
- Hearnshaw SJ, Edwards MJ, Stevenson CE, Lawson DM, Maxwell A. A new crystal structure of the bifunctional antibiotic simocyclinone D8 bound to DNA gyrase gives fresh insight into the mechanism of inhibition. J Mol Biol. 2014 Mar 1. pii: S0022-2836(14)00099-0. doi:, 10.1016/j.jmb.2014.02.017. PMID:24594357 doi:http://dx.doi.org/10.1016/j.jmb.2014.02.017
