1cm9
From Proteopedia
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{{STRUCTURE_1cm9| PDB=1cm9 | SCENE= }} | {{STRUCTURE_1cm9| PDB=1cm9 | SCENE= }} | ||
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===CRYSTAL STRUCTURE OF VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II=== | ===CRYSTAL STRUCTURE OF VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II=== | ||
| + | {{ABSTRACT_PUBMED_11041848}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/VMI2_HHV8 VMI2_HHV8]] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:011041848</ref><references group="xtra"/> | + | <ref group="xtra">PMID:011041848</ref><references group="xtra"/><references/> |
[[Category: Human herpesvirus 8]] | [[Category: Human herpesvirus 8]] | ||
[[Category: Fernandez, E J.]] | [[Category: Fernandez, E J.]] | ||
Revision as of 06:32, 10 April 2014
Contents |
CRYSTAL STRUCTURE OF VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II
Template:ABSTRACT PUBMED 11041848
Function
[VMI2_HHV8] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
About this Structure
1cm9 is a 2 chain structure with sequence from Human herpesvirus 8. Full crystallographic information is available from OCA.
Reference
- Fernandez EJ, Wilken J, Thompson DA, Peiper SC, Lolis E. Comparison of the structure of vMIP-II with eotaxin-1, RANTES, and MCP-3 suggests a unique mechanism for CCR3 activation. Biochemistry. 2000 Oct 24;39(42):12837-44. PMID:11041848
