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4p3f
From Proteopedia
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| - | + | {{STRUCTURE_4p3f| PDB=4p3f | SCENE= }} | |
| + | ===Structure of the human SRP68-RBD=== | ||
| + | {{ABSTRACT_PUBMED_24700861}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/SRP68_HUMAN SRP68_HUMAN]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. | ||
| - | + | ==About this Structure== | |
| + | [[4p3f]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P3F OCA]. | ||
| - | + | ==Reference== | |
| + | <ref group="xtra">PMID:024700861</ref><references group="xtra"/><references/> | ||
| + | [[Category: Grotwinkel, J T.]] | ||
| + | [[Category: Sinning, I.]] | ||
| + | [[Category: Wild, K.]] | ||
| + | [[Category: Rna binding protein]] | ||
Revision as of 09:44, 16 April 2014
Contents |
Structure of the human SRP68-RBD
Template:ABSTRACT PUBMED 24700861
Function
[SRP68_HUMAN] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
About this Structure
4p3f is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Grotwinkel JT, Wild K, Segnitz B, Sinning I. SRP RNA remodeling by SRP68 explains its role in protein translocation. Science. 2014 Apr 4;344(6179):101-4. doi: 10.1126/science.1249094. PMID:24700861 doi:http://dx.doi.org/10.1126/science.1249094
