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1fsg
From Proteopedia
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===TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH 9-DEAZAGUANINE, ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP) AND TWO MG2+ IONS=== | ===TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH 9-DEAZAGUANINE, ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP) AND TWO MG2+ IONS=== | ||
| + | {{ABSTRACT_PUBMED_11188695}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/HGXR_TOXGO HGXR_TOXGO]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to the N(9) of hypoxanthine, guanine or xanthine.<ref>PMID:11188695</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1fsg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii_rh Toxoplasma gondii rh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSG OCA]. | |
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| + | ==See Also== | ||
| + | *[[Phosphoribosyltransferase|Phosphoribosyltransferase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011188695</ref><references group="xtra"/><references/> |
[[Category: Hypoxanthine phosphoribosyltransferase]] | [[Category: Hypoxanthine phosphoribosyltransferase]] | ||
| - | [[Category: Toxoplasma gondii]] | + | [[Category: Toxoplasma gondii rh]] |
[[Category: Borhani, D W.]] | [[Category: Borhani, D W.]] | ||
[[Category: Heroux, A.]] | [[Category: Heroux, A.]] | ||
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[[Category: Glycosyltransferase]] | [[Category: Glycosyltransferase]] | ||
[[Category: Purine salvage]] | [[Category: Purine salvage]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 10:44, 16 April 2014
Contents |
TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH 9-DEAZAGUANINE, ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP) AND TWO MG2+ IONS
Template:ABSTRACT PUBMED 11188695
Function
[HGXR_TOXGO] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to the N(9) of hypoxanthine, guanine or xanthine.[1]
About this Structure
1fsg is a 2 chain structure with sequence from Toxoplasma gondii rh. Full crystallographic information is available from OCA.
See Also
Reference
- Heroux A, White EL, Ross LJ, Kuzin AP, Borhani DW. Substrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis. Structure. 2000 Dec 15;8(12):1309-18. PMID:11188695
