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1ttl
From Proteopedia
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{{STRUCTURE_1ttl| PDB=1ttl | SCENE= }} | {{STRUCTURE_1ttl| PDB=1ttl | SCENE= }} | ||
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===Omega-conotoxin GVIA, a N-type calcium channel blocker=== | ===Omega-conotoxin GVIA, a N-type calcium channel blocker=== | ||
| + | {{ABSTRACT_PUBMED_15166237}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/CXO6_CONGE CXO6_CONGE]] Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav). | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1ttl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Conus_geographus Conus geographus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TTL OCA]. | |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:015166237</ref><references group="xtra"/><references/> | |
[[Category: Conus geographus]] | [[Category: Conus geographus]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Adams, D J.]] | [[Category: Adams, D J.]] | ||
[[Category: Beedle, A M.]] | [[Category: Beedle, A M.]] | ||
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[[Category: Disulfide rich]] | [[Category: Disulfide rich]] | ||
[[Category: Four loop framework]] | [[Category: Four loop framework]] | ||
| - | + | [[Category: Toxin]] | |
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Revision as of 08:41, 23 April 2014
Contents |
Omega-conotoxin GVIA, a N-type calcium channel blocker
Template:ABSTRACT PUBMED 15166237
Function
[CXO6_CONGE] Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
About this Structure
1ttl is a 1 chain structure with sequence from Conus geographus. Full experimental information is available from OCA.
Reference
- Mould J, Yasuda T, Schroeder CI, Beedle AM, Doering CJ, Zamponi GW, Adams DJ, Lewis RJ. The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels. J Biol Chem. 2004 Aug 13;279(33):34705-14. Epub 2004 May 27. PMID:15166237 doi:10.1074/jbc.M310848200
