Saposin
From Proteopedia
(Difference between revisions)
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== 3D Structures of Saposin == | == 3D Structures of Saposin == | ||
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| + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
===Saposin A=== | ===Saposin A=== | ||
| - | [[2dob]] – hSapA residues 60-140 – human | + | [[2dob]] – hSapA residues 60-140 – human<br /> |
| + | [[4ddj]] – hSapA + LDAO<br /> | ||
===Saposin B=== | ===Saposin B=== | ||
Revision as of 06:22, 30 April 2014
Saposin (Sap) is a small protein which functions as activator of lipid-degrading enzymes. They act by isolating the lipid substrate from the membrane. Sap is synthesized as a precursor – prosaposin – which contain 4 SapB active domains and 2 SapA domains which are cleaved off. For more details see Molecular Playground/Saposin C.
3D Structures of Saposin
Updated on 30-April-2014
Saposin A
2dob – hSapA residues 60-140 – human
4ddj – hSapA + LDAO
Saposin B
1n69 – hSapB + lipid
Saposin C
1m12, 1sn6 – hSapC – NMR
2gtg, 2qyp, 2z9a – hSapC residues 311-391
Saposin D
3bqp, 3bqq, 2r1q, 2rb3 - hSapD residues 405-484
2r0r - hSapD residues 407-484 (mutant)
