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2ljq

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[[Image:2ljq.jpg|left|200px]]
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==(C9S, C14S)-leucocin A==
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<StructureSection load='2ljq' size='340' side='right' caption='[[2ljq]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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== Structural highlights ==
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[[2ljq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leuconostoc_gelidum Leuconostoc gelidum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LJQ OCA]. <br>
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<b>Related:</b> [[2ljt|2ljt]]<br>
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<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
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== Publication Abstract from PubMed ==
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Bridge not required: The disulfide bridge in the antibacterial peptide leucocin A was replaced with two Ser or two Leu residues. The double leucine mutant was found to be active, and elucidation of its 3D structure showed that the two leucines interact to hold the N- and C-terminal domains together.
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Substitution of a Conserved Disulfide in the Type IIa Bacteriocin, Leucocin A, with L-Leucine and L-Serine Residues: Effects on Activity and Three-Dimensional Structure.,Sit CS, Lohans CT, van Belkum MJ, Campbell CD, Miskolzie M, Vederas JC Chembiochem. 2012 Jan 2;13(1):35-8. doi: 10.1002/cbic.201100634. Epub 2011, Nov 25. PMID:22121114<ref>PMID:22121114</ref>
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The line below this paragraph, containing "STRUCTURE_2ljq", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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{{STRUCTURE_2ljq| PDB=2ljq | SCENE= }}
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===(C9S, C14S)-leucocin A===
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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== References ==
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<references/>
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_22121114}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22121114 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22121114}}
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==About this Structure==
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[[2ljq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leuconostoc_gelidum Leuconostoc gelidum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LJQ OCA].
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==Reference==
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<ref group="xtra">PMID:022121114</ref><references group="xtra"/>
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[[Category: Leuconostoc gelidum]]
[[Category: Leuconostoc gelidum]]
[[Category: Belkum, M J.van.]]
[[Category: Belkum, M J.van.]]

Revision as of 08:42, 30 April 2014

(C9S, C14S)-leucocin A

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