User:Jaakko Itkonen
From Proteopedia
(Difference between revisions)
| Line 27: | Line 27: | ||
Fig. 1 X-ray structure of a truncated form of hCNTF (2-187) | Fig. 1 X-ray structure of a truncated form of hCNTF (2-187) | ||
| + | ==Structure== | ||
| + | Overview | ||
| + | |||
| + | |||
| + | ==Disease== | ||
==References== | ==References== | ||
Revision as of 11:48, 7 May 2014
- Full Real Name: Jaakko Matias Itkonen
- Position: Student
- Institution (NO ABBREVIATIONS): University of Helsinki, Faculty Of Pharmacy, Division of Pharmaceutical Biosciences
- City, State/Province, Country: Helsinki, Finland
- Field of Expertise or Study: Pharmacy
Contents |
Introduction
Ciliary neutrophic factor (CNTF) is a nerve growth factor belonging to the IL-6 family of neuropoietic cytokines. Other members of this family include leukaemie inhibitory factor (LIF), IL-6, IL-11 and oncostatin M (Wang 2012). CNTF is a roughly 22.7 kDa protein consisting of a single peptide chain of 200 amino acid residues. Like many other cytokines, CNTF is folded into a bundle of four anti-parallel α-helices (A-D), where helices A-B and C-D are connected by two cross-over loops and helices B-C by one short loop.
Fig. 1 X-ray structure of a truncated form of hCNTF (2-187)
Structure
Overview
