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2m8a
From Proteopedia
(Difference between revisions)
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| - | + | ==2'F-ANA/2'F-RNA alternated sequences== | |
| - | + | <StructureSection load='2m8a' size='340' side='right' caption='[[2m8a]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[2m8a]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M8A FirstGlance]. <br> | ||
| + | </td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AF2:2-DEOXY-2-FLUOROADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>AF2</scene>, <scene name='pdbligand=CFL:4-AMINO-1-(2-DEOXY-2-FLUORO-5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)PYRIMIDIN-2(1H)-ONE'>CFL</scene>, <scene name='pdbligand=CFZ:2-DEOXY-2-FLUOROCYTIDINE+5-(DIHYDROGEN+PHOSPHATE)'>CFZ</scene>, <scene name='pdbligand=GF2:2-DEOXY-2-FLUOROGUANOSINE+5-(DIHYDROGEN+PHOSPHATE)'>GF2</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene>, <scene name='pdbligand=UFT:2-DEOXY-2-FLUOROURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>UFT</scene></td></tr> | ||
| + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2m84|2m84]]</td></tr> | ||
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m8a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m8a RCSB], [http://www.ebi.ac.uk/pdbsum/2m8a PDBsum]</span></td></tr> | ||
| + | <table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Polarizing CHO hydrogen bonds: The structure of oligonucleotides containing alternating and contiguous tracts of 2'F-RNA and 2'F-ANA nucleotides reveals that nonconventional FCHO hydrogen bonds have a strong stabilizing effect on 2'-fluorinated duplexes. | ||
| - | + | Backbone FCHO Hydrogen Bonds in 2'F-Substituted Nucleic Acids.,Martin-Pintado N, Deleavey GF, Portella G, Campos-Olivas R, Orozco M, Damha MJ, Gonzalez C Angew Chem Int Ed Engl. 2013 Sep 23. doi: 10.1002/anie.201305710. PMID:24115468<ref>PMID:24115468</ref> | |
| - | + | ||
| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Campos, R.]] | [[Category: Campos, R.]] | ||
[[Category: Damha, M.]] | [[Category: Damha, M.]] | ||
Revision as of 07:06, 21 May 2014
2'F-ANA/2'F-RNA alternated sequences
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