This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4d0z
From Proteopedia
m (Protected "4d0z" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | ''' | + | ==GalNAc-T2 crystal soaked with UDP-5SGalNAc, mEA2 and manganese (Higher resolution dataset)== |
| - | + | <StructureSection load='4d0z' size='340' side='right' caption='[[4d0z]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4d0z]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D0Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D0Z FirstGlance]. <br> | |
| - | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BBK:2-(ACETYLAMINO)-2-DEOXY-5-THIO-ALPHA-D-GALACTOPYRANOSE'>BBK</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HWU:(2R,3R,4R,5R,6R)-3-(ACETYLAMINO)-4,5-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-THIOPYRAN-2-YL+[(2R,3S,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+DIPHOSPHATE'>HWU</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br> | |
| - | + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4d0t|4d0t]], [[4d11|4d11]]</td></tr> | |
| - | + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Polypeptide_N-acetylgalactosaminyltransferase Polypeptide N-acetylgalactosaminyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.41 2.4.1.41] </span></td></tr> | |
| + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d0z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d0z RCSB], [http://www.ebi.ac.uk/pdbsum/4d0z PDBsum]</span></td></tr> | ||
| + | <table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Polypeptide N-acetylgalactosaminyltransferase]] | ||
| + | [[Category: Clausen, H.]] | ||
| + | [[Category: Companon, I.]] | ||
| + | [[Category: Corzana, F.]] | ||
| + | [[Category: Hurtado-Guerrero, R.]] | ||
| + | [[Category: Iglesias-Fernandez, J.]] | ||
| + | [[Category: Kong, Y.]] | ||
| + | [[Category: Lira-Navarrete, E.]] | ||
| + | [[Category: Peregrina, J M.]] | ||
| + | [[Category: Pinto, B M.]] | ||
| + | [[Category: Rovira, C.]] | ||
| + | [[Category: Vocadlo, D.]] | ||
| + | [[Category: Zandberg, W F.]] | ||
| + | [[Category: Acetamido group]] | ||
| + | [[Category: Bi-bi kinetic mechanism]] | ||
| + | [[Category: Qm/mm metadynamic]] | ||
| + | [[Category: Retaining galnac-t2]] | ||
| + | [[Category: Substrate specificity]] | ||
| + | [[Category: Substrate-guided sni-type reaction]] | ||
| + | [[Category: Transferase-peptide complex]] | ||
Revision as of 10:00, 28 May 2014
GalNAc-T2 crystal soaked with UDP-5SGalNAc, mEA2 and manganese (Higher resolution dataset)
| |||||||||||
Categories: Polypeptide N-acetylgalactosaminyltransferase | Clausen, H. | Companon, I. | Corzana, F. | Hurtado-Guerrero, R. | Iglesias-Fernandez, J. | Kong, Y. | Lira-Navarrete, E. | Peregrina, J M. | Pinto, B M. | Rovira, C. | Vocadlo, D. | Zandberg, W F. | Acetamido group | Bi-bi kinetic mechanism | Qm/mm metadynamic | Retaining galnac-t2 | Substrate specificity | Substrate-guided sni-type reaction | Transferase-peptide complex
