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1s2r

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[[Image:1s2r.png|left|200px]]
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==A High Resolution Crystal Structure of [d(CGCAAATTTGCG)]2==
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<StructureSection load='1s2r' size='340' side='right' caption='[[1s2r]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1s2r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S2R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1S2R FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene><br>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s2r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1s2r RCSB], [http://www.ebi.ac.uk/pdbsum/1s2r PDBsum]</span></td></tr>
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<table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of [d(CGCAAATTTGCG)]2 has been determined to 1.5 A resolution, representing the first high-resolution structure of this DNA fragment. The ion interactions are novel. A spermine molecule replaces a Mg2+ observed in analogous structures. Unlike lower-resolution structures, the minor groove is narrow and the major groove lacks extra Watson-Crick hydrogen bonds. In addition, a monolayer of solvent sites, including a "spine of hydration", is visible in the minor groove. The crystal of [d(CGCAAATTTGCG)]2 was grown from a solution containing spermine, magnesium, and lithium. The conformation recapitulates that of "monovalent-minus" DNA.
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{{STRUCTURE_1s2r| PDB=1s2r | SCENE= }}
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High-resolution structure of an extended A-tract: [d(CGCAAATTTGCG)]2.,Woods KK, Maehigashi T, Howerton SB, Sines CC, Tannenbaum S, Williams LD J Am Chem Soc. 2004 Dec 1;126(47):15330-1. PMID:15563130<ref>PMID:15563130</ref>
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===A High Resolution Crystal Structure of [d(CGCAAATTTGCG)]2===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_15563130}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1s2r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S2R OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:015563130</ref><references group="xtra"/>
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[[Category: Howerton, S B.]]
[[Category: Howerton, S B.]]
[[Category: Maehigashi, T.]]
[[Category: Maehigashi, T.]]

Revision as of 07:00, 9 June 2014

A High Resolution Crystal Structure of [d(CGCAAATTTGCG)]2

1s2r, resolution 1.53Å

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