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4pyq

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'''Unreleased structure'''
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==Humanized rat apo-COMT in complex with a ureido-benzamidine==
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<StructureSection load='4pyq' size='340' side='right' caption='[[4pyq]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
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The entry 4pyq is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4pyq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PYQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PYQ FirstGlance]. <br>
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Authors: Ehler, A., Benz, J., Schlatter, D., Rudolph, M.G.
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2X1:4-({[3-(AMINOMETHYL)PHENYL]CARBAMOYL}AMINO)BENZENECARBOXIMIDAMIDE'>2X1</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p7k|4p7k]], [[4p7f|4p7f]], [[4p7g|4p7g]], [[4p7j|4p7j]], [[4pyj|4pyj]], [[4pyi|4pyi]], [[4pyk|4pyk]], [[4pyl|4pyl]], [[4pym|4pym]], [[4pyn|4pyn]], [[4pyo|4pyo]]</td></tr>
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Description: Humanized rat apo-COMT in complex with a ureido-benzamidine
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_O-methyltransferase Catechol O-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.6 2.1.1.6] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pyq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pyq RCSB], [http://www.ebi.ac.uk/pdbsum/4pyq PDBsum]</span></td></tr>
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<table>
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__TOC__
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</StructureSection>
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[[Category: Catechol O-methyltransferase]]
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[[Category: Benz, J.]]
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[[Category: Ehler, A.]]
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[[Category: Rudolph, M G.]]
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[[Category: Schlatter, D.]]
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[[Category: Alternative initiation]]
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[[Category: Catecholamine metabolism]]
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[[Category: Cell membrane]]
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[[Category: Conformational change]]
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[[Category: Enzyme mechanism]]
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[[Category: Magnesium]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Methyltransferase]]
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[[Category: Neurotransmitter degradation]]
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[[Category: Phosphoprotein]]
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[[Category: Signal-anchor]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Transmembrane anchor]]

Revision as of 08:58, 11 June 2014

Humanized rat apo-COMT in complex with a ureido-benzamidine

4pyq, resolution 1.39Å

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