Single-stranded DNA-binding protein
From Proteopedia
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[[4gs3]] – SSB N terminal – ''Thermoanaerobacter tengcongensis''<br /> | [[4gs3]] – SSB N terminal – ''Thermoanaerobacter tengcongensis''<br /> | ||
[[3dm3]] – SSB A domain – ''Methancaldococcus jannaschii''<br /> | [[3dm3]] – SSB A domain – ''Methancaldococcus jannaschii''<br /> | ||
| + | [[1vqe]], [[1yha]], [[1vqb]] – F1SSB – Enterobacteria phage F1<br /> | ||
| + | [[2gn5]] – M13SSB – Enterobacteria phage M13<br /> | ||
| + | [[2gva]], [[2gvb]] – M13SSB (mutant) - NMR<br /> | ||
| + | [[1vqa]], [[1vqc]], [[1vqd]], [[1vqe]], [[1vqf]], [[1vqg]], [[1vqh]], [[1vqi]], [[1vqj]], [[1ae2]], [[1ae3]], [[1gkh]], [[1SSB]] – F1SSB (mutant) <br /> | ||
===SSB complex with ssDNA=== | ===SSB complex with ssDNA=== | ||
Revision as of 06:46, 29 June 2014
Single-stranded DNA-binding protein (SSB) binds to single-stranded regions of DNA (ssDNA) to protect it from annealing, prevention of secondary structure formation and digestion. SSB binds to DNA in a sequence-independent manner. The binding of SSB enables processes like replication, DNA repair and recombination to occur. SSB can form complexes with specific genome maintenance proteins helping their activities. See also Single stranded binding protein.
3D Structures of single-stranded DNA-binding protein
Updated on 29-June-2014
1gpc – SSB gp32 – Enterobacteria phage T4
2a1k – SSB gp32 – Enterobacteria phage RB69
1je5 – SSB – Enterobacteria phage T7
1adu, 1adv, 1anv – SSB C terminal – human adenovirus 5
1urj – SSB – human herpesvirus 1
1pfs – SSB (mutant) – Pseudomonas phage PF3 - NMR
3ull, 1s3o, 2dud – hSSB residues 16-148 – human
1fgu – hSSB central domain
2b29 – hSSB N terminal domain
4ipc, 4ipd, 4ipg – hSSB N terminal domain (mutant)
1kaw – EcSSB chymotryptic domain – Escherichia coli
1qvc, 1sru – EcSSB
1o7i – SSB residues 1-119 – Sulfolobus solfataricus
1ue1, 1ue5, 1ue7, 1ue6 – SSB – Mycobacterium tuberculosis
1x3e, 1x3f, 1x3g – MsSSB – Mycobacterium smegmatis
1se8 – DrSSB – Deinococcus radiodurans
4exw – SSB DdrB – Deinococcus geothermalis
1z9f – SSB – Thermotoga maritima
2cwa – SSB – Thermus thermophilus
2fxq, 2ihe – TaSSB – Thermus aquaticus
2ihf – TaSSB (mutant)
2hql – SSB – Mycoplasma pneumoniae
3eiv – ScSSB – Streptomyces coelicolor
4dam – ScSSB (mutant)
3lgj, 3pgz – SSB – Bartonella henselae
3afp, 3afq – SSB – Mycobacterium leprae
3tqy – SSB – Coxiella burnetii
3tek – SSB N terminal – Thermoproteus tenax
4gs3 – SSB N terminal – Thermoanaerobacter tengcongensis
3dm3 – SSB A domain – Methancaldococcus jannaschii
1vqe, 1yha, 1vqb – F1SSB – Enterobacteria phage F1
2gn5 – M13SSB – Enterobacteria phage M13
2gva, 2gvb – M13SSB (mutant) - NMR
1vqa, 1vqc, 1vqd, 1vqe, 1vqf, 1vqg, 1vqh, 1vqi, 1vqj, 1ae2, 1ae3, 1gkh, 1SSB – F1SSB (mutant)
SSB complex with ssDNA
1eyg – EcSSB chymotryptic domain + ssDNA
1eqq – EcSSB + ssDNA
2vw9 – HpSSB + ssDNA
3vdy – SSB + ssDNA – Bacillus subtilis
3a5u – MsSSB chymotryptic domain + ssDNA
3udg – DrSSB + ssDNA
SSB other complexes
3ufm, 3uf7 – DrSSB C terminal + uracil-DNA glycosylase
2b3g – hSSB N terminal domain + tumor suppressor P53
4nb3 – hSSB N terminal domain (mutant) + polypeptide
4ijh, 4ijl, 4iph, 4luo, 4luv, 4luz, 4lw1, 4lwc, 4o0a – hSSB N terminal domain (mutant) + inhibitor
