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Protegrin

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<StructureSection load="1pg1" size="400" color="" frame="true" spin="on" Scene= align="right" caption="NMR structure of pig protegrin 1, [[1pg1]]" >
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<StructureSection load="1pg1" size="400" color="" spin="on" Scene= caption="NMR structure of pig protegrin 1, [[1pg1]]" >
[[Image:1pg1.png|left|200px]]
[[Image:1pg1.png|left|200px]]

Revision as of 07:34, 20 August 2014

NMR structure of pig protegrin 1, 1pg1

Drag the structure with the mouse to rotate

References

Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes., Fahrner RL, Dieckmann T, Harwig SS, Lehrer RI, Eisenberg D, Feigon J, Chem Biol. 1996 Jul;3(7):543-50. PMID:8807886

3D structures of protegrin

Updated on 20-August-2014

1pg1, 1zy6 – pPRO1 – pig – NMR
1n5h, 1n5p – pPRO3 cathelin-like domain – NMR
1kwi, 1lxe, 1pfp – pPRO3 cathelin-like domain

  1. Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity., Lehrer RI, Barton A, Daher KA, Harwig SS, Ganz T, Selsted ME., J Clin Invest. 1989 Aug;84(2):553-61. PMID: 2668334
  2. Susceptibility of Chlamydia trachomatis to protegrins and defensins., Yasin B, Harwig SS, Lehrer RI, Wagar EA., Infect Immun. 1996 Mar;64(3):709-13. PMID: 8641770
  3. Membrane channel formation by antimicrobial protegrins., Sokolov Y, Mirzabekov T, Martin DW, Lehrer RI, Kagan BL, Biochim Biophys Acta. 1999 Aug 20;1420(1-2):23-9. PMID:10446287
  4. Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity, D A Steinberg, M A Hurst, C A Fujii, A H Kung, J F Ho, F C Cheng, D J Loury, and J C Fiddes, Antimicrob Agents Chemother. 1997 August; 41(8): 1738–1742. PMCID: PMC163996
  5. NPG1. EBI QuickGO. http://www.ebi.ac.uk/QuickGO/GProtein?ac=P32194
  6. Protein: Protegrin 1 (PG1) from Pig (Sus scrofa). Structural Classification of Proteins. http://scop.mrc-lmb.cam.ac.uk/scop/data/scop.b.ba.e.b.f.b.html


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