Semaphorin
From Proteopedia
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'''Semaphorin''' (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics. | '''Semaphorin''' (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics. | ||
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==3D structures of semaphorin== | ==3D structures of semaphorin== |
Revision as of 09:26, 20 August 2014
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Semaphorin (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics.
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3D structures of semaphorin
Update February 2013
SEMA 3
1q47, 4gz8 – mSEMA 3A – mouse
4gza – mSEMA 3A + plexin A2 + neuropilin 1
SEMA 4
1olz – hSEMA 4D extracellular domain – human
3ol2 - hSEMA 4D extracellular domain + plexin-B1
SEMA 6
3afc, 3okw - mSEMA 6A extracellular domain
3al8 - mSEMA 6A + plexin-A2