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Tumor necrosis factor receptor

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== Function ==
== Function ==
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'''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF. TNFR family contains several members and superfamily (TNFRSF) members. The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains. '''TNFRSF 6''' is called '''Fas'''; '''TNFRSF 10B''' is called '''Dr5'''; '''TNFRSF 21''' is called '''Dr6'''; '''TNFRSF 11A''' is called '''RANK'''; '''TNFRSF 18''' is called '''GITRL'''.
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'''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF. TNFR family contains several members and superfamily (TNFRSF) members. The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains.<br />
 +
* '''TNFRSF 6''' is called '''Fas''';<br />
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* '''TNFRSF 10B''' is called '''Dr5''';<br />
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* '''TNFRSF 21''' is called '''Dr6''';<br />
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* '''TNFRSF 11A''' is called '''RANK''';<br />
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* '''TNFRSF 18''' is called '''GITRL'''.
== Disease ==
== Disease ==

Revision as of 08:43, 21 August 2014

Structure of human TNFRSF-18 extracellular domain (PDB code 2q1m).

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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