Cholesterol esterase
From Proteopedia
(Difference between revisions)
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
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| + | ===Cholesterol esterase=== | ||
[[1akn]] – bChoE – bovine<br /> | [[1akn]] – bChoE – bovine<br /> | ||
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[[1f6w]] – hChoE catalytic domain (mutant) | [[1f6w]] – hChoE catalytic domain (mutant) | ||
| - | ==Cholesterol esterase complex with bile acids== | + | ===Cholesterol esterase complex with bile acids=== |
[[1cle]] – CcChoE + cholesteryl linoleate – ''Candida cylindracea''<br /> | [[1cle]] – CcChoE + cholesteryl linoleate – ''Candida cylindracea''<br /> | ||
Revision as of 07:32, 26 August 2014
Cholesterol esterase (ChoE) also named bile-acid activated lipase catalyzes the hydrolytic cleavage of cholesterol, other sterol esters and triglycerides. Deficiency of this enzyme causes Wolman’s disease and cholesteryl ester storage disease.
3D structures of cholesterol esterase
Updated on 26-August-2014
Cholesterol esterase
1akn – bChoE – bovine
2bce – bChoE (mutant)
1jmy – hChoE - human
1f6w – hChoE catalytic domain (mutant)
Cholesterol esterase complex with bile acids
1cle – CcChoE + cholesteryl linoleate – Candida cylindracea
1llf – CcChoE + tricosanoic acid
1aql – bChoE + taurocholate
