1dul
From Proteopedia
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| - | [[Image:1dul.jpg|left|200px]] | + | [[Image:1dul.jpg|left|200px]] |
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| - | '''STRUCTURE OF THE RIBONUCLEOPROTEIN CORE OF THE E. COLI SIGNAL RECOGNITION PARTICLE''' | + | {{Structure |
| + | |PDB= 1dul |SIZE=350|CAPTION= <scene name='initialview01'>1dul</scene>, resolution 1.80Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene> and <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''STRUCTURE OF THE RIBONUCLEOPROTEIN CORE OF THE E. COLI SIGNAL RECOGNITION PARTICLE''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1DUL is a [ | + | 1DUL is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DUL OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of the ribonucleoprotein core of the signal recognition particle., Batey RT, Rambo RP, Lucast L, Rha B, Doudna JA, Science. 2000 Feb 18;287(5456):1232-9. PMID:[http:// | + | Crystal structure of the ribonucleoprotein core of the signal recognition particle., Batey RT, Rambo RP, Lucast L, Rha B, Doudna JA, Science. 2000 Feb 18;287(5456):1232-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10678824 10678824] |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: tetraloop]] | [[Category: tetraloop]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:44:41 2008'' |
Revision as of 08:44, 20 March 2008
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| , resolution 1.80Å | |||||||
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| Ligands: | and | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
STRUCTURE OF THE RIBONUCLEOPROTEIN CORE OF THE E. COLI SIGNAL RECOGNITION PARTICLE
Overview
The signal recognition particle (SRP), a protein-RNA complex conserved in all three kingdoms of life, recognizes and transports specific proteins to cellular membranes for insertion or secretion. We describe here the 1.8 angstrom crystal structure of the universal core of the SRP, revealing protein recognition of a distorted RNA minor groove. Nucleotide analog interference mapping demonstrates the biological importance of observed interactions, and genetic results show that this core is functional in vivo. The structure explains why the conserved residues in the protein and RNA are required for SRP assembly and defines a signal sequence recognition surface composed of both protein and RNA.
About this Structure
1DUL is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Crystal structure of the ribonucleoprotein core of the signal recognition particle., Batey RT, Rambo RP, Lucast L, Rha B, Doudna JA, Science. 2000 Feb 18;287(5456):1232-9. PMID:10678824
Page seeded by OCA on Thu Mar 20 10:44:41 2008
