Phosphoglycerate dehydrogenase
From Proteopedia
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==3D structures of phosphoglycerate dehydrogenase== | ==3D structures of phosphoglycerate dehydrogenase== | ||
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[[1ygy]], [[3dc2]] – MtPGDH – ''Mycobacterium tuberculosis''<br /> | [[1ygy]], [[3dc2]] – MtPGDH – ''Mycobacterium tuberculosis''<br /> | ||
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[[3k5p]] - PGDH (mutant) – ''Brucella melitensis'' | [[3k5p]] - PGDH (mutant) – ''Brucella melitensis'' | ||
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[[1sc6]], [[2p9c]], [[2p9e]], [[2p9g]] - EcPGDH (mutant) + NAD – ''Escherichia coli''<br /> | [[1sc6]], [[2p9c]], [[2p9e]], [[2p9g]] - EcPGDH (mutant) + NAD – ''Escherichia coli''<br /> | ||
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[[3ddn]] - MtPGDH + hydroxypyruvic acid phosphate | [[3ddn]] - MtPGDH + hydroxypyruvic acid phosphate | ||
| - | + | ===PGDH ternary complex=== | |
[[1psd]] - EcPGDH + serine + NAD <br /> | [[1psd]] - EcPGDH + serine + NAD <br /> | ||
Revision as of 08:39, 2 September 2014
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Phosphoglycerate dehydrogenase (PGDH) catalyzes the conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate. This is the first step of serine biosynthesis. NAD is used as cofactor. In some cancer cells there is an elevation in PGDH level.
Contents |
3D structures of phosphoglycerate dehydrogenase
PDGH
1ygy, 3dc2 – MtPGDH – Mycobacterium tuberculosis
3evt - PGDH – Lactobacillus plantarum
3gg9 - PGDH – Ralstonia solanacearum
3k5p - PGDH (mutant) – Brucella melitensis
PGDH binary complex
1sc6, 2p9c, 2p9e, 2p9g - EcPGDH (mutant) + NAD – Escherichia coli
1yba - EcPGDH + NAD
1wwk - PGDH + NAD – Pyrococcus horikoshii
2g76 - PGDH + NAD – human
2ekl - PGDH + NAD – Sulfolobus tokodaii
3ddn - MtPGDH + hydroxypyruvic acid phosphate
PGDH ternary complex
1psd - EcPGDH + serine + NAD
2pa3 - EcPGDH (mutant) + serine + NAD
