This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1fat

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1fat.gif|left|200px]]<br /><applet load="1fat" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1fat.gif|left|200px]]
-
caption="1fat, resolution 2.8&Aring;" />
+
 
-
'''PHYTOHEMAGGLUTININ-L'''<br />
+
{{Structure
 +
|PDB= 1fat |SIZE=350|CAPTION= <scene name='initialview01'>1fat</scene>, resolution 2.8&Aring;
 +
|SITE= <scene name='pdbsite=CAA:Ca+Binding+Site+In+Chain+A'>CAA</scene>, <scene name='pdbsite=CAB:Ca+Binding+Site+In+Chain+B'>CAB</scene>, <scene name='pdbsite=CAC:Ca+Binding+Site+In+Chain+C'>CAC</scene>, <scene name='pdbsite=CAD:Ca+Binding+Site+In+Chain+D'>CAD</scene>, <scene name='pdbsite=MNA:Mn+Binding+Site+In+Chain+A'>MNA</scene>, <scene name='pdbsite=MNB:Mn+Binding+Site+In+Chain+B'>MNB</scene>, <scene name='pdbsite=MNC:Mn+Binding+Site+In+Chain+C'>MNC</scene> and <scene name='pdbsite=MND:Mn+Binding+Site+In+Chain+D'>MND</scene>
 +
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''PHYTOHEMAGGLUTININ-L'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1FAT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Phaseolus_vulgaris Phaseolus vulgaris] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=CAA:Ca+Binding+Site+In+Chain+A'>CAA</scene>, <scene name='pdbsite=CAB:Ca+Binding+Site+In+Chain+B'>CAB</scene>, <scene name='pdbsite=CAC:Ca+Binding+Site+In+Chain+C'>CAC</scene>, <scene name='pdbsite=CAD:Ca+Binding+Site+In+Chain+D'>CAD</scene>, <scene name='pdbsite=MNA:Mn+Binding+Site+In+Chain+A'>MNA</scene>, <scene name='pdbsite=MNB:Mn+Binding+Site+In+Chain+B'>MNB</scene>, <scene name='pdbsite=MNC:Mn+Binding+Site+In+Chain+C'>MNC</scene> and <scene name='pdbsite=MND:Mn+Binding+Site+In+Chain+D'>MND</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FAT OCA].
+
1FAT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Phaseolus_vulgaris Phaseolus vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FAT OCA].
==Reference==
==Reference==
-
The crystallographic structure of phytohemagglutinin-L., Hamelryck TW, Dao-Thi MH, Poortmans F, Chrispeels MJ, Wyns L, Loris R, J Biol Chem. 1996 Aug 23;271(34):20479-85. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8702788 8702788]
+
The crystallographic structure of phytohemagglutinin-L., Hamelryck TW, Dao-Thi MH, Poortmans F, Chrispeels MJ, Wyns L, Loris R, J Biol Chem. 1996 Aug 23;271(34):20479-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8702788 8702788]
[[Category: Phaseolus vulgaris]]
[[Category: Phaseolus vulgaris]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 22: Line 31:
[[Category: plant defense protein]]
[[Category: plant defense protein]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:36:45 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:06:41 2008''

Revision as of 09:06, 20 March 2008

Image:1fat.gif


PDB ID 1fat

Drag the structure with the mouse to rotate
, resolution 2.8Å
Sites: , , , , , , and
Ligands: , and
Coordinates: save as pdb, mmCIF, xml



PHYTOHEMAGGLUTININ-L


Overview

The structure of phytohemagglutinin-L (PHA-L), a leucoagglutinating seed lectin from Phaseolus vulgaris, has been solved with molecular replacement using the coordinates of lentil lectin as model, and refined at a resolution of 2.8 A. The final R-factor of the structure is 20.0%. The quaternary structure of the PHA-L tetramer differs from the structures of the concanavalin A and peanut lectin tetramers, but resembles the structure of the soybean agglutinin tetramer. PHA-L consists of two canonical legume lectin dimers that pack together through the formation of a close contact between two beta-strands. Of the two covalently bound oligosaccharides per monomer, only one GlcNAc residue per monomer is visible in the electron density. In this article we describe the structure of PHA-L, and we discuss the putative position of the high affinity adenine-binding site present in a number of legume lectins. A comparison with transthyretin, a protein that shows a remarkable resemblance to PHA-L, gives further ground to our proposal.

About this Structure

1FAT is a Single protein structure of sequence from Phaseolus vulgaris. Full crystallographic information is available from OCA.

Reference

The crystallographic structure of phytohemagglutinin-L., Hamelryck TW, Dao-Thi MH, Poortmans F, Chrispeels MJ, Wyns L, Loris R, J Biol Chem. 1996 Aug 23;271(34):20479-85. PMID:8702788

Page seeded by OCA on Thu Mar 20 11:06:41 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1fat"
Personal tools