1g0x

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1g0x.gif|left|200px]]<br /><applet load="1g0x" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1g0x.gif|left|200px]]
-
caption="1g0x, resolution 2.10&Aring;" />
+
 
-
'''CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF LIR-1 (ILT2)'''<br />
+
{{Structure
 +
|PDB= 1g0x |SIZE=350|CAPTION= <scene name='initialview01'>1g0x</scene>, resolution 2.10&Aring;
 +
|SITE=
 +
|LIGAND=
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF LIR-1 (ILT2)'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1G0X is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G0X OCA].
+
1G0X is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G0X OCA].
==Reference==
==Reference==
-
Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2)., Chapman TL, Heikema AP, West AP Jr, Bjorkman PJ, Immunity. 2000 Nov;13(5):727-36. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11114384 11114384]
+
Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2)., Chapman TL, Heikema AP, West AP Jr, Bjorkman PJ, Immunity. 2000 Nov;13(5):727-36. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11114384 11114384]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 20: Line 29:
[[Category: immunoglobulin fold]]
[[Category: immunoglobulin fold]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:44:47 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:16:38 2008''

Revision as of 09:16, 20 March 2008

Image:1g0x.gif


PDB ID 1g0x

Drag the structure with the mouse to rotate
, resolution 2.10Å
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF LIR-1 (ILT2)


Overview

LIR-1 is an inhibitory receptor that recognizes class I MHC molecules and the human cytomegalovirus class I homolog UL18. Here, we report the 2.1 A resolution crystal structure of the ligand binding portion of LIR-1 (domains 1 and 2 [D1D2]) and localize the binding region for UL18. LIR-1 D1D2 is composed of two immunoglobulin-like domains arranged at an acute angle to form a bent structure resembling the structures of natural killer inhibitory receptors (KIRs). The LIR-1 binding site comprises a portion of D1 distant from the interdomain hinge region that constitutes the KIR binding site, consistent with differences in LIR-1 and KIR recognition properties and functions.

About this Structure

1G0X is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2)., Chapman TL, Heikema AP, West AP Jr, Bjorkman PJ, Immunity. 2000 Nov;13(5):727-36. PMID:11114384

Page seeded by OCA on Thu Mar 20 11:16:38 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1g0x"
Personal tools