1v0m

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[[Image:1v0m.png|left|200px]]
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==XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 7.5==
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<StructureSection load='1v0m' size='340' side='right' caption='[[1v0m]], [[Resolution|resolution]] 1.07&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1v0m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V0M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V0M FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene><br>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=XDN:PIPERIDINE-3,4,5-TRIOL'>XDN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e0v|1e0v]], [[1e0w|1e0w]], [[1e0x|1e0x]], [[1knl|1knl]], [[1knm|1knm]], [[1mc9|1mc9]], [[1od8|1od8]], [[1v0l|1v0l]], [[1v0k|1v0k]], [[1v0n|1v0n]], [[1xas|1xas]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v0m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v0m RCSB], [http://www.ebi.ac.uk/pdbsum/1v0m PDBsum]</span></td></tr>
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v0/1v0m_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The atomic resolution structures of xylobiose-derived isofagomine and xylobiose-derived deoxynojirimycin in complex with the xylanase Xyn10A from Streptomyces lividans reveal undistorted (4)C(1) chair conformed sugars and, in the case of the deoxynojirimycin analogue, suggest unusual pK(a) changes of the enzyme's catalytic machinery upon binding.
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{{STRUCTURE_1v0m| PDB=1v0m | SCENE= }}
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Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A.,Gloster TM, Williams SJ, Roberts S, Tarling CA, Wicki J, Withers SG, Davies GJ Chem Commun (Camb). 2004 Aug 21;(16):1794-5. Epub 2004 Jul 23. PMID:15306887<ref>PMID:15306887</ref>
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===XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 7.5===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_15306887}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1v0m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V0M OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:015306887</ref><references group="xtra"/>
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[[Category: Endo-1,4-beta-xylanase]]
[[Category: Endo-1,4-beta-xylanase]]
[[Category: Streptomyces lividans]]
[[Category: Streptomyces lividans]]

Revision as of 18:23, 29 September 2014

XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 7.5

1v0m, resolution 1.07Å

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OCA

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