1vow

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{Large structure}}
+
==Crystal structure of five 70s ribosomes from Escherichia Coli in complex with protein Y. This file contains the 50s subunit of one 70s ribosome. The entire crystal structure contains five 70s ribosomes and is described in remark 400.==
-
{{STRUCTURE_1vow| PDB=1vow | SCENE= }}
+
<StructureSection load='1vow' size='340' side='right' caption='[[1vow]], [[Resolution|resolution]] 11.50&Aring;' scene=''>
-
===Crystal structure of five 70s ribosomes from Escherichia Coli in complex with protein Y. This file contains the 50s subunit of one 70s ribosome. The entire crystal structure contains five 70s ribosomes and is described in remark 400.===
+
== Structural highlights ==
-
{{ABSTRACT_PUBMED_15502846}}
+
<table><tr><td colspan='2'>[[1vow]] is a 32 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VOW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VOW FirstGlance]. <br>
 +
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
 +
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1voq|1voq]], [[1vor|1vor]], [[1vos|1vos]], [[1vou|1vou]], [[1vov|1vov]], [[1vox|1vox]], [[1voy|1voy]], [[1voz|1voz]], [[1vp0|1vp0]]</td></tr>
 +
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vow OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vow RCSB], [http://www.ebi.ac.uk/pdbsum/1vow PDBsum]</span></td></tr>
 +
<table>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vo/1vow_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
During environmental stress, organisms limit protein synthesis by storing inactive ribosomes that are rapidly reactivated when conditions improve. Here we present structural and biochemical data showing that protein Y, an Escherichia coli stress protein, fills the tRNA- and mRNA-binding channel of the small ribosomal subunit to stabilize intact ribosomes. Protein Y inhibits translation initiation during cold shock but not at normal temperatures. Furthermore, protein Y competes with conserved translation initiation factors that, in bacteria, are required for ribosomal subunit dissociation. The mechanism used by protein Y to reduce translation initiation during stress and quickly release ribosomes for renewed translation initiation may therefore occur widely in nature.
-
==About this Structure==
+
Structural basis for the control of translation initiation during stress.,Vila-Sanjurjo A, Schuwirth BS, Hau CW, Cate JH Nat Struct Mol Biol. 2004 Nov;11(11):1054-9. Epub 2004 Oct 24. PMID:15502846<ref>PMID:15502846</ref>
-
[[1vow]] is a 32 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VOW OCA].
+
-
==See Also==
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
*[[Ribosomal protein L1|Ribosomal protein L1]]
+
</div>
-
*[[Ribosomal protein L11|Ribosomal protein L11]]
+
-
*[[Ribosomal protein L13|Ribosomal protein L13]]
+
-
*[[Ribosomal protein L14|Ribosomal protein L14]]
+
-
*[[Ribosomal protein L15|Ribosomal protein L15]]
+
-
*[[Ribosomal protein L16|Ribosomal protein L16]]
+
-
*[[Ribosomal protein L17|Ribosomal protein L17]]
+
-
*[[Ribosomal protein L18|Ribosomal protein L18]]
+
-
*[[Ribosomal protein L19|Ribosomal protein L19]]
+
-
*[[Ribosomal protein L2|Ribosomal protein L2]]
+
-
*[[Ribosomal protein L20|Ribosomal protein L20]]
+
-
*[[Ribosomal protein L21|Ribosomal protein L21]]
+
-
*[[Ribosomal protein L22|Ribosomal protein L22]]
+
-
*[[Ribosomal protein L23|Ribosomal protein L23]]
+
-
*[[Ribosomal protein L24|Ribosomal protein L24]]
+
-
*[[Ribosomal protein L27|Ribosomal protein L27]]
+
-
*[[Ribosomal protein L29|Ribosomal protein L29]]
+
-
*[[Ribosomal protein L3|Ribosomal protein L3]]
+
-
*[[Ribosomal protein L30|Ribosomal protein L30]]
+
-
*[[Ribosomal protein L31|Ribosomal protein L31]]
+
-
*[[Ribosomal protein L32|Ribosomal protein L32]]
+
-
*[[Ribosomal protein L33|Ribosomal protein L33]]
+
-
*[[Ribosomal protein L34|Ribosomal protein L34]]
+
-
*[[Ribosomal protein L35|Ribosomal protein L35]]
+
-
*[[Ribosomal protein L36|Ribosomal protein L36]]
+
-
*[[Ribosomal protein L4|Ribosomal protein L4]]
+
-
*[[Ribosomal protein L5|Ribosomal protein L5]]
+
-
*[[Ribosomal protein L6|Ribosomal protein L6]]
+
-
*[[Ribosomal protein L9|Ribosomal protein L9]]
+
-
==Reference==
+
==See Also==
-
<ref group="xtra">PMID:015502846</ref><references group="xtra"/>
+
*[[Ribosome 3D structures|Ribosome 3D structures]]
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Cate, J H.]]
[[Category: Cate, J H.]]

Revision as of 21:45, 29 September 2014

Crystal structure of five 70s ribosomes from Escherichia Coli in complex with protein Y. This file contains the 50s subunit of one 70s ribosome. The entire crystal structure contains five 70s ribosomes and is described in remark 400.

1vow, resolution 11.50Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1vow"
Views
Personal tools
Navigation
Toolbox