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3p99

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<StructureSection load='3p99' size='340' side='right' caption='[[3p99]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='3p99' size='340' side='right' caption='[[3p99]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3p99]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P99 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3p99]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_(trypanozoon)_brucei Trypanosoma (trypanozoon) brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P99 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=LNP:(3ALPHA,9BETA,10ALPHA,13ALPHA)-30-CYCLOPROPYLIDENELANOST-7-EN-3-OL'>LNP</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=LNP:(3ALPHA,9BETA,10ALPHA,13ALPHA)-30-CYCLOPROPYLIDENELANOST-7-EN-3-OL'>LNP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3g1q|3g1q]], [[3gw9|3gw9]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3g1q|3g1q]], [[3gw9|3gw9]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYP51, Tb11.02.4080 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma brucei])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYP51, Tb11.02.4080 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma (Trypanozoon) brucei])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p99 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p99 RCSB], [http://www.ebi.ac.uk/pdbsum/3p99 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p99 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p99 RCSB], [http://www.ebi.ac.uk/pdbsum/3p99 PDBsum]</span></td></tr>
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<table>
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</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Sterol 14-demethylase]]
[[Category: Sterol 14-demethylase]]
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[[Category: Trypanosoma brucei]]
 
[[Category: Hargrove, T Y.]]
[[Category: Hargrove, T Y.]]
[[Category: Lepesheva, G I.]]
[[Category: Lepesheva, G I.]]
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[[Category: Waterman, M R]]
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[[Category: Waterman, M R.]]
[[Category: Wawrzak, Z.]]
[[Category: Wawrzak, Z.]]
[[Category: Cyp51]]
[[Category: Cyp51]]

Revision as of 05:50, 8 October 2014

Sterol 14alpha-demethylase (CYP51) from Trypanosoma brucei in complex with delta7-14alpha-methylene-cyclopropyl-dihydrolanosterol

3p99, resolution 3.00Å

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