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2vrw

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<StructureSection load='2vrw' size='340' side='right' caption='[[2vrw]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='2vrw' size='340' side='right' caption='[[2vrw]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vrw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VRW OCA]. <br>
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<table><tr><td colspan='2'>[[2vrw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VRW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e96|1e96]], [[1i4d|1i4d]], [[1foe|1foe]], [[1mh1|1mh1]], [[1i4l|1i4l]], [[1he1|1he1]], [[1ryf|1ryf]], [[1k1z|1k1z]], [[1ryh|1ryh]], [[1hh4|1hh4]], [[1gcp|1gcp]], [[1g4u|1g4u]], [[2fju|2fju]], [[1f5x|1f5x]], [[1i4t|1i4t]], [[1gcq|1gcq]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e96|1e96]], [[1i4d|1i4d]], [[1foe|1foe]], [[1mh1|1mh1]], [[1i4l|1i4l]], [[1he1|1he1]], [[1ryf|1ryf]], [[1k1z|1k1z]], [[1ryh|1ryh]], [[1hh4|1hh4]], [[1gcp|1gcp]], [[1g4u|1g4u]], [[2fju|2fju]], [[1f5x|1f5x]], [[1i4t|1i4t]], [[1gcq|1gcq]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vrw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vrw RCSB], [http://www.ebi.ac.uk/pdbsum/2vrw PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vrw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vrw RCSB], [http://www.ebi.ac.uk/pdbsum/2vrw PDBsum]</span></td></tr>
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</table>
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<table>
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== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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Crucial structural role for the PH and C1 domains of the Vav1 exchange factor.,Rapley J, Tybulewicz VL, Rittinger K EMBO Rep. 2008 Jul;9(7):655-61. Epub 2008 May 30. PMID:18511940<ref>PMID:18511940</ref>
Crucial structural role for the PH and C1 domains of the Vav1 exchange factor.,Rapley J, Tybulewicz VL, Rittinger K EMBO Rep. 2008 Jul;9(7):655-61. Epub 2008 May 30. PMID:18511940<ref>PMID:18511940</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==

Revision as of 05:56, 10 October 2014

CRITICAL STRUCTURAL ROLE FOR THE PH AND C1 DOMAINS OF THE VAV1 EXCHANGE FACTOR

2vrw, resolution 1.85Å

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