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2k98

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[[Image:2k98.png|left|200px]]
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==Helical hairpin structure of potent antimicrobial peptide MSI-594 in the presence of Lipopolysaccharide micelle==
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<StructureSection load='2k98' size='340' side='right' caption='[[2k98]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2k98]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K98 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K98 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k98 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k98 RCSB], [http://www.ebi.ac.uk/pdbsum/2k98 PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Essential understanding: Elucidation of structural requirements and interactions of antimicrobial peptides with lipopolysaccharide (LPS) are essential to understand the mechanism of action of antimicrobial peptides. The highly active antimicrobial peptide MSI-594 (see figure for electrostatic potential surface) acquires a novel helical hairpin structure in complex with LPS. The structure and interactions of MSI-594 with LPS presented here provide important insights into the mechanism of outer membrane permeabilization by antimicrobial peptides.
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{{STRUCTURE_2k98| PDB=2k98 | SCENE= }}
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Helical Hairpin Structure of a Potent Antimicrobial Peptide MSI-594 in Lipopolysaccharide Micelles by NMR Spectroscopy.,Bhunia A, Ramamoorthy A, Bhattacharjya S Chemistry. 2009 Jan 29;15(9):2036-2040. PMID:19180607<ref>PMID:19180607</ref>
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===Helical hairpin structure of potent antimicrobial peptide MSI-594 in the presence of Lipopolysaccharide micelle===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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{{ABSTRACT_PUBMED_19180607}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[2k98]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K98 OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:019180607</ref><references group="xtra"/>
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[[Category: Bhattacharjya, S.]]
[[Category: Bhattacharjya, S.]]
[[Category: Bhunia, A.]]
[[Category: Bhunia, A.]]

Revision as of 15:33, 12 October 2014

Helical hairpin structure of potent antimicrobial peptide MSI-594 in the presence of Lipopolysaccharide micelle

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