Sandbox ceg1p Steven Paris
From Proteopedia
(Difference between revisions)
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== Function of Ceg1p and the Cet1-Ceg1 mRNA Capping Complex == | == Function of Ceg1p and the Cet1-Ceg1 mRNA Capping Complex == | ||
Ceg1p is an mRNA guanylyltransferase in ''Saccharomyces cerevisiae'' that forms a heterotetramer with the RNA triphosphatase cet1p which is called the mRNA capping apparatus. This complex is recruited by RNA polymerase II (RNAP-II) and performs the first two steps in the 5’-guanisine capping mechanism of mRNA. Cet1p hydrolyzes the 5’-triphosphate end of the mRNA, then Ceg1p attaches a guanine monophosphate (GMP) to the 5’-diphosphate end (1). | Ceg1p is an mRNA guanylyltransferase in ''Saccharomyces cerevisiae'' that forms a heterotetramer with the RNA triphosphatase cet1p which is called the mRNA capping apparatus. This complex is recruited by RNA polymerase II (RNAP-II) and performs the first two steps in the 5’-guanisine capping mechanism of mRNA. Cet1p hydrolyzes the 5’-triphosphate end of the mRNA, then Ceg1p attaches a guanine monophosphate (GMP) to the 5’-diphosphate end (1). | ||
| - | == | + | == Structure of Ceg1p and Interactions with Cet1p in the Capping Apparatus == |
== Relevance == | == Relevance == | ||
Revision as of 00:43, 14 October 2014
Ceg1p mRNA Guanylyltransferase
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
