4rbj

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'''Unreleased structure'''
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==Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites==
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<StructureSection load='4rbj' size='340' side='right' caption='[[4rbj]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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The entry 4rbj is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4rbj]] is a 25 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RBJ FirstGlance]. <br>
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Authors: Polikanov, Y.S., Szal, T., Jiang, F., Gupta, P., Matsuda, R., Shiozuka, M., Steitz, T.A., Vazquez-Laslop, Nora, Mankin, A.S.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NEG:NEGAMYCIN'>NEG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=4SU:4-THIOURIDINE-5-MONOPHOSPHATE'>4SU</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=7MG:7N-METHYL-8-HYDROGUANOSINE-5-MONOPHOSPHATE'>7MG</scene>, <scene name='pdbligand=MIA:2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5-MONOPHOSPHATE'>MIA</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene></td></tr>
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Description: Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rbh|4rbh]], [[4rbi|4rbi]], [[4rbk|4rbk]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rbj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rbj RCSB], [http://www.ebi.ac.uk/pdbsum/4rbj PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Thermus thermophilus]]
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[[Category: Gupta, P.]]
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[[Category: Jiang, F.]]
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[[Category: Mankin, A S.]]
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[[Category: Matsuda, R.]]
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[[Category: Polikanov, Y S.]]
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[[Category: Shiozuka, M.]]
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[[Category: Steitz, T A.]]
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[[Category: Szal, T.]]
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[[Category: Vazquez-Laslop, Nora]]
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[[Category: 30s subunit with negamycin]]
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[[Category: 50s subunit of the 2nd 70s ribosome in the asu]]
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[[Category: 70s ribosome]]
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[[Category: And e-site trnas of the 2nd 70s ribosome in the asu]]
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[[Category: Antibiotic]]
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[[Category: Deacylated a-]]
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[[Category: Functional complex of bacterial 70s ribosome with antibiotic negamycin]]
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[[Category: Inhibition of translation]]
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[[Category: Miscoding]]
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[[Category: Mrna]]
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[[Category: Negamycin]]
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[[Category: P-]]
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[[Category: Ribosome-antibiotic complex]]
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[[Category: Translocation inhibitor]]

Revision as of 11:02, 20 October 2014

Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites

4rbj, resolution 2.70Å

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