7,8-dihydro-8-oxoguanine triphosphatase

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== Structural highlights ==
== Structural highlights ==
 +
</StructureSection>
==3D structures of 7,8-dihydro-8-oxoguanine triphosphatase==
==3D structures of 7,8-dihydro-8-oxoguanine triphosphatase==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
-
[[4jzs]] – BsDGTP (mutant) – ''Bacillus subtilis''<br />
+
*DGTP
-
[[4jzt]] – BsDGTP (mutant) + GTP <br />
+
-
[[4jzu]], [[4jzv]] – BsDGTP + RNA triphosphorylated<br />
+
-
===MutT===
+
**[[4jzs]] – BsDGTP (mutant) – ''Bacillus subtilis''<br />
 +
**[[4jzt]] – BsDGTP (mutant) + GTP <br />
 +
**[[4jzu]], [[4jzv]] – BsDGTP + RNA triphosphorylated<br />
-
[[3a6s]] – EcMutT – ''Escherichia coli'' <br />
+
*MutT
-
[[1mut]] – EcMutT - NMR<br />
+
-
[[3a6v]] – EcMutT + Mn<br />
+
-
[[1tum]] – EcMutT + Mg + ATP derivative - NMR<br />
+
-
[[3a6t]] – EcMutT + oxoG <br />
+
-
[[3a6u]] – EcMutT + Mn + oxoG <br />
+
-
[[1ppx]], [[1pun]], [[1puq]], [[1pus]] – EcMutT + Mg + oxoG - NMR<br />
+
-
===MTH1===
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**[[3a6s]] – EcMutT – ''Escherichia coli'' <br />
 +
**[[1mut]] – EcMutT - NMR<br />
 +
**[[3a6v]] – EcMutT + Mn<br />
 +
**[[1tum]] – EcMutT + Mg + ATP derivative - NMR<br />
 +
**[[3a6t]] – EcMutT + oxoG <br />
 +
**[[3a6u]] – EcMutT + Mn + oxoG <br />
 +
**[[1ppx]], [[1pun]], [[1puq]], [[1pus]] – EcMutT + Mg + oxoG - NMR<br />
-
[[3q93]], [[3zr1]] – hMTH1 - human <br />
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*MTH1
-
[[1iry]] – hMTH1 - NMR<br />
+
-
[[3zr0]] – hMTH1 + oxoG<br />
+
-
[[3whw]], [[4n1t]], [[4n1u]] – hMTH1 + inhibitor<br />
+
-
[[4c9w]], [[4c9x]] – hMTH1 + anti-cancer drug<br />
+
 +
**[[3q93]], [[3zr1]] – hMTH1 - human <br />
 +
**[[1iry]] – hMTH1 - NMR<br />
 +
**[[3zr0]] – hMTH1 + oxoG<br />
 +
**[[3whw]], [[4n1t]], [[4n1u]] – hMTH1 + inhibitor<br />
 +
**[[4c9w]], [[4c9x]] – hMTH1 + anti-cancer drug<br />
 +
}}
== References ==
== References ==

Revision as of 12:40, 11 November 2014

Structure of human MTH1 complex with 8-oxo-dGTP (stick model) and sulfate (PDB code 3zr0).

Drag the structure with the mouse to rotate

3D structures of 7,8-dihydro-8-oxoguanine triphosphatase

Updated on 11-November-2014

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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