Alpha-lytic protease

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'''Alpha-lytic protease''' (ALP) is a bacterial serine protease of the chymotrypsin family. ALP is a two-domain enzyme. One domain is a large pro region that catalyzes the folding of the protease. The second domain is the protease domain.
'''Alpha-lytic protease''' (ALP) is a bacterial serine protease of the chymotrypsin family. ALP is a two-domain enzyme. One domain is a large pro region that catalyzes the folding of the protease. The second domain is the protease domain.
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</StructureSection>
== 3D Structures of alpha-lytic protease ==
== 3D Structures of alpha-lytic protease ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===ALP protease domain===
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*ALP protease domain
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[[2alp]], [[1p09]], [[1tal]], [[2ull]], [[1boq]], [[1ssz]], [[2h5c]], [[1ssx]] – LeALP – ''Lysobacter enzymogenes'' <BR />
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**[[2alp]], [[1p09]], [[1tal]], [[2ull]], [[1boq]], [[1ssz]], [[2h5c]], [[1ssx]] – LeALP – ''Lysobacter enzymogenes'' <BR />
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[[1gba]], [[1gbe]], [[1gbj]], [[3urc]], [[3urd]], [[3ure]] – LeALP (mutant) <BR />
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**[[1gba]], [[1gbe]], [[1gbj]], [[3urc]], [[3urd]], [[3ure]] – LeALP (mutant) <BR />
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[[1p01]], [[1p02]], [[1p03]], [[1p04]], [[1p05]], [[1p06]], [[1p10]], [[2lpr]], [[3lpr]], [[5lpr]], [[6lpr]], [[7lpr]], [[8lpr]], [[9lpr]], [[2h5d]] – LeALP + boronic acid inhibitor <BR />
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**[[1p01]], [[1p02]], [[1p03]], [[1p04]], [[1p05]], [[1p06]], [[1p10]], [[2lpr]], [[3lpr]], [[5lpr]], [[6lpr]], [[7lpr]], [[8lpr]], [[9lpr]], [[2h5d]] – LeALP + boronic acid inhibitor <BR />
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[[1gbb]], [[1gbc]], [[1gbd]], [[1gbf]], [[1gbh]], [[1gbi]], [[1gbk]], [[1gbl]], [[1gbm]] – LeALP (mutant) + boronic acid inhibitor <BR />
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**[[1gbb]], [[1gbc]], [[1gbd]], [[1gbf]], [[1gbh]], [[1gbi]], [[1gbk]], [[1gbl]], [[1gbm]] – LeALP (mutant) + boronic acid inhibitor <BR />
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[[1p11]], [[1p12]] – LeALP + phosphonate esther inhibitor <BR />
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**[[1p11]], [[1p12]] – LeALP + phosphonate esther inhibitor <BR />
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[[3qgj]] – LeALP + peptide <BR />
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**[[3qgj]] – LeALP + peptide <BR />
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===ALP including pro region===
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*ALP including pro region
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[[2pro]], [[1qrx]] – LeALP pro region <BR />
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**[[2pro]], [[1qrx]] – LeALP pro region <BR />
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[[1qq4]], [[1qrw]], [[3m7t]], [[3m7u]] – LeALP pro region (mutant) <BR />
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**[[1qq4]], [[1qrw]], [[3m7t]], [[3m7u]] – LeALP pro region (mutant) <BR />
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[[3pro]] – LeALP (mutant) + pro region <BR />
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**[[3pro]] – LeALP (mutant) + pro region <BR />
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[[4pro]] – LeALP (mutant) + pro region (mutant) <BR />
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**[[4pro]] – LeALP (mutant) + pro region (mutant) <BR />
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}}
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[[Category: Topic Page]]

Revision as of 11:06, 16 November 2014

Structure of alpha-lytic protease complex with boronic acid inhibitor and sulfate (PDB entry 1p05)

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3D Structures of alpha-lytic protease

Updated on 16-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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