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4ng6
From Proteopedia
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| - | ''' | + | ==The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates== |
| - | + | <StructureSection load='4ng6' size='340' side='right' caption='[[4ng6]], [[Resolution|resolution]] 2.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ng6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NG6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NG6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RIS:1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE+BIS-PHOSPHONIC+ACID'>RIS</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kfa|4kfa]], [[4kqs|4kqs]], [[1yq7|1yq7]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ng6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ng6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ng6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ng6 PDBsum]</span></td></tr> | |
| + | </table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Barnett, B L]] | ||
| + | [[Category: Dunford, J E]] | ||
| + | [[Category: Ebetino, F H]] | ||
| + | [[Category: Evdokimov, A]] | ||
| + | [[Category: Kavanagh, K L]] | ||
| + | [[Category: Kwaasi, A A]] | ||
| + | [[Category: Muniz, J R.C]] | ||
| + | [[Category: Oppermann, U]] | ||
| + | [[Category: Pilka, E]] | ||
| + | [[Category: Russell, R G.G]] | ||
| + | [[Category: Tsoumpra, M K]] | ||
| + | [[Category: Walter, R L]] | ||
| + | [[Category: Alpha-helical prenyltransferase]] | ||
| + | [[Category: Bisphosphonate]] | ||
| + | [[Category: Cholesterol synthesis]] | ||
| + | [[Category: Isoprene biosynthesis]] | ||
| + | [[Category: Isoprenoid pathway]] | ||
| + | [[Category: Lipid synthesis]] | ||
| + | [[Category: Steroid biosynthesis]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 12:49, 19 November 2014
The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates
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Categories: Barnett, B L | Dunford, J E | Ebetino, F H | Evdokimov, A | Kavanagh, K L | Kwaasi, A A | Muniz, J R.C | Oppermann, U | Pilka, E | Russell, R G.G | Tsoumpra, M K | Walter, R L | Alpha-helical prenyltransferase | Bisphosphonate | Cholesterol synthesis | Isoprene biosynthesis | Isoprenoid pathway | Lipid synthesis | Steroid biosynthesis | Transferase
