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DNA methyltransferase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===Methylguanine DNMT===
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*Methylguanine DNMT
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[[1sfe]] – O6-methylguanine DNMT C terminal – ''Escherichia coli''
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**[[1sfe]] – O6-methylguanine DNMT C terminal – ''Escherichia coli''
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[[1qnt]], [[1eh6]], [[3llr]] - hO6-methylguanine DNMT – human
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**[[1qnt]], [[1eh6]], [[3llr]] - hO6-methylguanine DNMT – human
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[[1t38]] - hO6-methylguanine DNMT (mutant) + DNA
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**[[1t38]] - hO6-methylguanine DNMT (mutant) + DNA
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[[1t39]], [[1yfh]] - hO6-methylguanine DNMT + DNA
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**[[1t39]], [[1yfh]] - hO6-methylguanine DNMT + DNA
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[[1eh7]] - hO6-methylguanine DNMT methylated
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**[[1eh7]] - hO6-methylguanine DNMT methylated
-
[[1eh8]] - hO6-methylguanine DNMT benzylated<br />
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**[[1eh8]] - hO6-methylguanine DNMT benzylated<br />
-
[[1mgt]]- O6-methylguanine DNMT – ''Thermococcus kodakarensis''<br />
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**[[1mgt]] - O6-methylguanine DNMT – ''Thermococcus kodakarensis''<br />
-
[[1wrj]] - O6-methylguanine DNMT - ''Sulfolobus tokodaii''
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**[[1wrj]] - O6-methylguanine DNMT - ''Sulfolobus tokodaii''
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[[2g7h]] - O6-methylguanine DNMT – ''Methanocaldococcus jannaschii''
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**[[2g7h]] - O6-methylguanine DNMT – ''Methanocaldococcus jannaschii''
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[[2kif]], [[2kim]] - O6-methylguanine DNMT – ''Vibrio parahaemolyticus'' - NMR<br />
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**[[2kif]], [[2kim]] - O6-methylguanine DNMT – ''Vibrio parahaemolyticus'' - NMR<br />
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[[4bhb]], [[4bhc]] - O6-methylguanine DNMT (mutant) – ''Mycobacterium tuberculosis''<br />
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**[[4bhb]], [[4bhc]] - O6-methylguanine DNMT (mutant) – ''Mycobacterium tuberculosis''<br />
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===Methylcytosine DNMT===
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*Methylcytosine DNMT
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[[2qrv]] - h-cytosine DNMT
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**[[2qrv]] - h-cytosine DNMT
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[[3epz]] - h-cytosine DNMT replecation foci-targeting sequence
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**[[3epz]] - h-cytosine DNMT replecation foci-targeting sequence
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[[3flg]] - h-cytosine DNMT ADD domain
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**[[3flg]] - h-cytosine DNMT ADD domain
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[[3a1a]] - h-cytosine DNMT PWWP domain
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**[[3a1a]] - h-cytosine DNMT PWWP domain
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[[1g55]] - h-cytosine DNMT2 (mutant)<br />
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**[[1g55]] - h-cytosine DNMT2 (mutant)<br />
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[[3qkj]] - h-cytosine DNMT 3β<br />
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**[[3qkj]] - h-cytosine DNMT 3β<br />
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[[3av4]], [[1khc]] - m-cytosine DNMT – mouse
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**[[3av4]], [[1khc]] - m-cytosine DNMT – mouse
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[[2uyc]], [[2uyh]], [[2uz4]] - Hh-cytosine DNMT (mutant) + DNA + SAH
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**[[2uyc]], [[2uyh]], [[2uz4]] - Hh-cytosine DNMT (mutant) + DNA + SAH
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[[3a1b]] - h-cytosine DNMT ADD domain + histone H3
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**[[3a1b]] - h-cytosine DNMT ADD domain + histone H3
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[[3pt6]], [[3pt9]], [[4da4]] – m-cytosine DNMT + DNA
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**[[3pt6]], [[3pt9]], [[4da4]] – m-cytosine DNMT + DNA
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[[3av5]] - m-cytosine DNMT + SAH
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**[[3av5]] - m-cytosine DNMT + SAH
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[[3av6]] - m-cytosine DNMT + SAM
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**[[3av6]] - m-cytosine DNMT + SAM
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[[3swr]] - h-cytosine DNMT + sinefungin
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**[[3swr]] - h-cytosine DNMT + sinefungin
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[[1boo]] - cytosine DNMT (mutant) – ''Proteus vulgaris''<br />
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**[[1boo]] - cytosine DNMT (mutant) – ''Proteus vulgaris''<br />
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[[3qv2]] - cytosine DNMT + SAH – ''Entamoeba histolytica''<br />
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**[[3qv2]] - cytosine DNMT + SAH – ''Entamoeba histolytica''<br />
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[[2uyc]], [[2uyh]], [[2uz4]], [[1fjx]] – Hh-cytosine DNMT (mutant) + DNA + SAH - ''Haemophilus haemolyticus''<br />
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**[[2uyc]], [[2uyh]], [[2uz4]], [[1fjx]] – Hh-cytosine DNMT (mutant) + DNA + SAH - ''Haemophilus haemolyticus''<br />
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[[2c7o]], [[2c7p]], [[2c7q]], [[2c7r]], [[3pta]] – Hh-cytosine DNMT + DNA + S-adenonosyl cysteine<br />
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**[[2c7o]], [[2c7p]], [[2c7q]], [[2c7r]], [[3pta]] – Hh-cytosine DNMT + DNA + S-adenonosyl cysteine<br />
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[[1hmy]] – Hh-cytosine Haeiii DNMT + SAM
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**[[1hmy]] – Hh-cytosine Haeiii DNMT + SAM
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**[[1m0e]] - Hh-cytosine DNMT (mutant) + DNA + inhibitor
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[[1m0e]] - Hh-cytosine DNMT (mutant) + DNA + inhibitor
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**[[2i9k]] - Hh-cytosine DNMT (mutant) + DNA
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[[2i9k]] - Hh-cytosine DNMT (mutant) + DNA
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**[[2hr1]] - Hh-cytosine DNMT + DNA + ADOHCY
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[[2hr1]] - Hh-cytosine DNMT + DNA + ADOHCY
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**[[2z6q]], [[2z6u]], [[2zcj]] - Hh-cytosine DNMT (mutant) + DNA + ADOHCY
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[[2z6q]], [[2z6u]], [[2zcj]] - Hh-cytosine DNMT (mutant) + DNA + ADOHCY
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**[[1svu]] - Hh-cytosine DNMT (mutant)<br />
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**[[4fsx]] – c-cytosine DNMT + SAH – corn<br />
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**[[4ft2]], [[4ft4]] – c-cytosine DNMT + histone H3 peptide<br />
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**[[4h0n]] - cytosine DNMT (mutant) – ''Spodoptera frugiperda''
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[[1svu]] - Hh-cytosine DNMT (mutant)<br />
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*Methyladenine DNMT
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[[4fsx]] – c-cytosine DNMT + SAH – corn<br />
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[[4ft2]], [[4ft4]] – c-cytosine DNMT + histone H3 peptide<br />
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[[4h0n]] - cytosine DNMT (mutant) – ''Spodoptera frugiperda''
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===Methyladenine DNMT===
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**[[1nw5]] – RsN6-adenine DNMT + SAM – ''Rhodobacter sphaeroides''
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[[1nw5]] – RsN6-adenine DNMT + SAM – ''Rhodobacter sphaeroides''
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**[[1nw6]] - RsN6-adenine DNMT + sinefungin<br />
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**[[1nw7]] - RsN6-adenine DNMT + SAH<br />
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[[1nw6]] - RsN6-adenine DNMT + sinefungin<br />
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**[[1nw8]] - RsN6-adenine DNMT (mutant)
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[[1nw7]] - RsN6-adenine DNMT + SAH<br />
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[[1nw8]] - RsN6-adenine DNMT (mutant)
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[[2ibs]], [[2ibt]], [[2ih2]], [[2ih4]], [[2ih5]], [[2np6]], [[2np7]], [[1g38]] - Ta-adenine DNMT Taqi + DNA + cofactor analog – ''Thermus aquaticus''<br />
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[[1aqi]] – Ta-adenine DNMT Taqi + SAH<br />
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[[1aqj]] – Ta-adenine DNMT Taqi + sinefugin<br />
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[[2adm]] - Ta-adenine DNMT Taqi + SAM<br />
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[[1g60]] - adenine DNMT + SAM – ''Moraxella bovis''
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**[[2ibs]], [[2ibt]], [[2ih2]], [[2ih4]], [[2ih5]], [[2np6]], [[2np7]], [[1g38]] - Ta-adenine DNMT Taqi + DNA + cofactor analog – ''Thermus aquaticus''<br />
 +
**[[1aqi]] – Ta-adenine DNMT Taqi + SAH<br />
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**[[1aqj]] – Ta-adenine DNMT Taqi + sinefugin<br />
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**[[2adm]] - Ta-adenine DNMT Taqi + SAM<br />
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**[[1g60]] - adenine DNMT + SAM – ''Moraxella bovis''
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}}

Revision as of 09:11, 24 November 2014

Template:STRUCTURE 1qnt

DNA methyltransferase (DNMT) catalyzes the transfer of methyl group to DNA. DNMT uses S-adenosyl methionine (SAM) as the methyl donor. The SAM analog S-adenosyl homocysteine (SAH) is a powerful inhibitor of DNMT.

3D Structures of DNA methyltransferase

Updated on 24-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/DNA_methyltransferase"
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