Elastase

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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=== MMP12 ===
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* MMP12 See [[Matrix metalloproteinase]]
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[[Matrix metalloproteinase]]
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* MMP16 See [[Matrix metalloproteinase]]
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=== MMP16 ===
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* ELA1
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[[Matrix metalloproteinase]]
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**[[3mty]], [[3mu0]], [[3mu1]], [[3mu4]], [[3mu5]], [[3mu8]], [[3mnb]], [[3mnc]], [[3mns]], [[3mnx]], [[3mo3]], [[3mo6]], [[3mo9]], [[3moc]], [[3e3t]], [[2v0b]], [[2g4t]], [[2g4u]], [[2de8]], [[2blo]], [[2blq]], [[2a7c]], [[2a7j]], [[1gvk]], [[1qnj]], [[1lvy]], [[3est]], [[1est]], [[2oqu]], [[3odd]], [[3odf]], [[2bdc]] – pELA1 – pig<br />
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**[[3hgn]] – pELA1+peptidyl inhibitor – neutron<br />
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**[[3hgp]], [[2cv3]], [[2bdb]], [[2bcd]], [[2h1u]], [[1mmj]], [[1h9l]], [[1nes]], [[4est]], [[5est]], [[8est]], [[7est]], [[6est]] - pELA1+peptidyl inhibitor<br />
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**[[1fzz]] – pELA1+ONO-6818<br />
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**[[1qr3]], [[1qgf]], [[1bru]], [[1hv7]], [[1btu]] – pELA1+cyclic inhibitor<br />
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**[[1okx]] – pELA1 + scyptolin<br />
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**[[1e34]], [[1e35]], [[1e36]], [[1e37]], [[1e38]] – pELA1-gamma-lactam<br />
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**[[1eai]] – pELA1+Ascaris inhibitor<br />
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**[[2d26]] – pELA1+α-1-antitrypsin<br />
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**[[1fle]] – pELA1+elafin<br />
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**[[1b0e]], [[1b0f]] – pELA1+MDL<br />
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**[[2v35]] – pELA1+JM54<br />
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**[[2iot]] – pELA1+clavulanic acid<br />
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**[[2de9]] – pELA1+tris<br />
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**[[1uvo]], [[1uvp]], [[1lka]], [[1lkb]] – pELA1+ions<br />
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**[[1gwa]] – pELA1+I3<br />
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**[[1uo6]], [[1c1m]] – pELA1+Xe<br />
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**[[1l0z]], [[1l1g]] - pELA1+Xe+Br<br />
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**[[2bb4]], [[2bd2]], [[2bd3]], [[2bd4]], [[2bd5]], [[2bd7]], [[2bd8]], [[2bd9]], [[1hax]], [[1hay]], [[1haz]], [[1hb0]], [[1qix]] – pELA1+beta-casomorphin-7<br />
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**[[2bda]] – pELA1+N-acetyl-NPI<br />
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**[[1mcv]] – pELA1+squash inhibitor<br />
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**[[1bma]] – pELA1+aminimide<br />
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**[[1elf]], [[1elg]] – pELA1+peptidyl hydroxylamine<br />
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**[[1eld]], [[1ele]], [[1elb]], [[1ela]], [[1elc]], [[2est]] – pELA1+anilide inhibitor<br />
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**[[1esa]], [[1esb]] – pELA1 intermediate<br />
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**[[1eas]], [[1eat]], [[1eau]] – pELA1+pyridine inhibitor<br />
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**[[1inc]] – pELA1+benzoxazinone<br />
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**[[1jim]], [[9est]], [[8est]] – pELA1+coumarin derivative<br />
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**[[2fo9]], [[2foa]], [[2fob]], [[2foc]], [[2fod]], [[2foe]], [[2fof]], [[2fog]], [[2foh]] – pELA1+solvent<br />
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**[[3dbk]] – PaELA+phophoramidon – Pseudomonas aeruginosa<br />
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**[[1u4g]] – PaELA+HPI<br />
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**[[1ezm]] - PaELA<br />
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**[[1elt]] – ELA - salmon<br />
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=== ELA1 ===
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* ELA2
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[[3mty]], [[3mu0]], [[3mu1]], [[3mu4]], [[3mu5]], [[3mu8]], [[3mnb]], [[3mnc]], [[3mns]], [[3mnx]], [[3mo3]], [[3mo6]], [[3mo9]], [[3moc]], [[3e3t]], [[2v0b]], [[2g4t]], [[2g4u]], [[2de8]], [[2blo]], [[2blq]], [[2a7c]], [[2a7j]], [[1gvk]], [[1qnj]], [[1lvy]], [[3est]], [[1est]], [[2oqu]], [[3odd]], [[3odf]], [[2bdc]] – pELA1 – pig<br />
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[[3hgn]] – pELA1+peptidyl inhibitor – neutron<br />
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[[3hgp]], [[2cv3]], [[2bdb]], [[2bcd]], [[2h1u]], [[1mmj]], [[1h9l]], [[1nes]], [[4est]], [[5est]], [[8est]], [[7est]], [[6est]] - pELA1+peptidyl inhibitor<br />
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[[1fzz]] – pELA1+ONO-6818<br />
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[[1qr3]], [[1qgf]], [[1bru]], [[1hv7]], [[1btu]] – pELA1+cyclic inhibitor<br />
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[[1okx]] – pELA1 + scyptolin<br />
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[[1e34]], [[1e35]], [[1e36]], [[1e37]], [[1e38]] – pELA1-gamma-lactam<br />
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[[1eai]] – pELA1+Ascaris inhibitor<br />
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[[2d26]] – pELA1+α-1-antitrypsin<br />
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[[1fle]] – pELA1+elafin<br />
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[[1b0e]], [[1b0f]] – pELA1+MDL<br />
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[[2v35]] – pELA1+JM54<br />
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[[2iot]] – pELA1+clavulanic acid<br />
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[[2de9]] – pELA1+tris<br />
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[[1uvo]], [[1uvp]], [[1lka]], [[1lkb]] – pELA1+ions<br />
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[[1gwa]] – pELA1+I3<br />
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[[1uo6]], [[1c1m]] – pELA1+Xe<br />
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[[1l0z]], [[1l1g]] - pELA1+Xe+Br<br />
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[[2bb4]], [[2bd2]], [[2bd3]], [[2bd4]], [[2bd5]], [[2bd7]], [[2bd8]], [[2bd9]], [[1hax]], [[1hay]], [[1haz]], [[1hb0]], [[1qix]] – pELA1+beta-casomorphin-7<br />
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[[2bda]] – pELA1+N-acetyl-NPI<br />
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[[1mcv]] – pELA1+squash inhibitor<br />
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[[1bma]] – pELA1+aminimide<br />
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[[1elf]], [[1elg]] – pELA1+peptidyl hydroxylamine<br />
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[[1eld]], [[1ele]], [[1elb]], [[1ela]], [[1elc]], [[2est]] – pELA1+anilide inhibitor<br />
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[[1esa]], [[1esb]] – pELA1 intermediate<br />
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[[1eas]], [[1eat]], [[1eau]] – pELA1+pyridine inhibitor<br />
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[[1inc]] – pELA1+benzoxazinone<br />
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[[1jim]], [[9est]], [[8est]] – pELA1+coumarin derivative<br />
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[[2fo9]], [[2foa]], [[2fob]], [[2foc]], [[2fod]], [[2foe]], [[2fof]], [[2fog]], [[2foh]] – pELA1+solvent<br />
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[[3dbk]] – PaELA+phophoramidon – Pseudomonas aeruginosa<br />
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[[1u4g]] – PaELA+HPI<br />
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[[1ezm]] - PaELA<br />
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[[1elt]] – ELA - salmon<br />
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=== ELA2 ===
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[[3q76]] – hELA2<br />
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[[3q77]] – hELA2+dihydropyrimidone inhibitor<br />
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[[2z7f]] – hELA2 peptidase domain +antileukoproteinase<br />
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[[2rg3]] – hELA2+sulfonic inhibitor<br />
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[[1h1b]], [[1ppg]], [[1hne]] – hELA2+inhibitor<br />
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[[1ppf]] – hELA2+ovomucoid<br />
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[[1b0f]] – hELA2+MDL101146<br />
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**[[3q76]] – hELA2<br />
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**[[3q77]] – hELA2+dihydropyrimidone inhibitor<br />
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**[[2z7f]] – hELA2 peptidase domain +antileukoproteinase<br />
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**[[2rg3]] – hELA2+sulfonic inhibitor<br />
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**[[1h1b]], [[1ppg]], [[1hne]] – hELA2+inhibitor<br />
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**[[1ppf]] – hELA2+ovomucoid<br />
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**[[1b0f]] – hELA2+MDL101146<br />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:10, 24 November 2014

Template:STRUCTURE 1esa

Elastase (ELA) is a chymotrypsin-like protease which breaks down proteins. The ELAs are numbered according to their genes. ELA2 (or PMN-ELA) is secreted by neutrophils during inflammation. For additional details see Serine Proteases.

3D structures of elastase

Updated on 24-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Guido Hansen, Jaime Prilusky

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