EPSP synthase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 5: Line 5:
The enzyme has <scene name='57/570585/Two_domains/1'>two domains</scene>, with the active site found in the interdomain cleft. There is a substantial structural change upon substrate binding, resulting in a <scene name='57/570585/Closed_formation/1'>closed formation</scene>. Glyphosate (also known as Roundup) occupies the binding site of the second substrate, phosphoenol pyruvate.
The enzyme has <scene name='57/570585/Two_domains/1'>two domains</scene>, with the active site found in the interdomain cleft. There is a substantial structural change upon substrate binding, resulting in a <scene name='57/570585/Closed_formation/1'>closed formation</scene>. Glyphosate (also known as Roundup) occupies the binding site of the second substrate, phosphoenol pyruvate.
 +
</StructureSection>
===3D structures of EPSP synthase ===
===3D structures of EPSP synthase ===
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 +
{{#tree:id=OrganizedByTopic|openlevels=0|
-
[[1eps]] – EcEPSP – ''Escherichia coli''<br />
+
*5-enolpyruvylshikimate 3-phosphate (EPSP) synthase
-
[[1p88]], [[1p89]] - EcEPSP N terminal - NMR<br />
+
-
[[1rf5]] - SpEPSP – ''Streptococcus pneumoniae''<br />
+
-
[[2bjb]], [[2o15]] – MtEPSP – ''Mycobacterium tuberculosis''<br />
+
-
[[2gg4]] – AgEPSP – ''Agrobacterium''<br />
+
-
[[3roi]], [[3tr1]], [[4gfp]] – CbEPSP – ''Coxiella burnetii''<br />
+
-
[[3ti2]] - VcEPSP N terminal – ''Vibrio cholerae''<br />
+
-
===EPSP synthase binary complex===
+
**[[1eps]] – EcEPSP – ''Escherichia coli''<br />
 +
**[[1p88]], [[1p89]] - EcEPSP N terminal - NMR<br />
 +
**[[1rf5]] - SpEPSP – ''Streptococcus pneumoniae''<br />
 +
**[[2bjb]], [[2o15]] – MtEPSP – ''Mycobacterium tuberculosis''<br />
 +
**[[2gg4]] – AgEPSP – ''Agrobacterium''<br />
 +
**[[3roi]], [[3tr1]], [[4gfp]] – CbEPSP – ''Coxiella burnetii''<br />
 +
**[[3ti2]] - VcEPSP N terminal – ''Vibrio cholerae''<br />
-
[[1g6t]] - EcEPSP + S3P <br />
+
*EPSP synthase binary complex
-
[[1mi4]], [[2qfq]], [[2qfs]], [[3fjx]], [[3fk0]] - EcEPSP (mutant) + S3P <br />
+
-
[[1q36]] - EcEPSP (mutant) + S3P derivative<br />
+
-
[[1x8r]], [[1x8t]] - EcEPSP + intermediate <br />
+
-
[[2aa9]] – EcEPSP + shikimate<br />
+
-
[[2pq9]] - EcEPSP + intermediate <br />
+
-
[[1rf4]] - SpEPSP + intermediate <br />
+
-
[[2o0b]], [[2o0d]] - MtEPSP + S3P <br />
+
-
[[2gg6]] - AgEPSP + S3P <br />
+
-
[[2pqb]], [[2pqc]], [[2pqd]] - AgEPSP + intermediate <br />
+
-
[[2o0x]] - MtEPSP + intermediate <br />
+
-
[[2o0z]] - MtEPSP + EPS <br />
+
-
[[4egr]] - CbEPSP + phosphoenolpyruvate<br />
+
-
===EPSP synthase ternary complex===
+
**[[1g6t]] - EcEPSP + S3P <br />
 +
**[[1mi4]], [[2qfq]], [[2qfs]], [[3fjx]], [[3fk0]] - EcEPSP (mutant) + S3P <br />
 +
**[[1q36]] - EcEPSP (mutant) + S3P derivative<br />
 +
**[[1x8r]], [[1x8t]] - EcEPSP + intermediate <br />
 +
**[[2aa9]] – EcEPSP + shikimate<br />
 +
**[[2pq9]] - EcEPSP + intermediate <br />
 +
**[[1rf4]] - SpEPSP + intermediate <br />
 +
**[[2o0b]], [[2o0d]] - MtEPSP + S3P <br />
 +
**[[2gg6]] - AgEPSP + S3P <br />
 +
**[[2pqb]], [[2pqc]], [[2pqd]] - AgEPSP + intermediate <br />
 +
**[[2o0x]] - MtEPSP + intermediate <br />
 +
**[[2o0z]] - MtEPSP + EPS <br />
 +
**[[4egr]] - CbEPSP + phosphoenolpyruvate<br />
-
[[1g6p]] - EcEPSP + S3P + glyphosate<br />
+
*EPSP synthase ternary complex
-
[[2qft]], [[2qfu]], [[3fjz]], [[3fk1]] - EcEPSP (mutant) + S3P + glyphosate<br />
+
-
[[2aay]] - EcEPSP + shikimate + glyphosate<br />
+
-
[[1rf6]] - SpEPSP + S3P + glyphosate<br />
+
-
[[2gga]] - AgEPSP + S3P + glyphosate<br />
+
-
[[4ggd]] - AgEPSP (mutant) + S3P + glyphosate<br />
+
-
[[2o0e]] - MtEPSP + S3P + phosphoenolpyruvate<br />
+
-
[[3nvs]] - VcEPSP + S3P + glyphosate <br />
+
-
[[3slh]] - CbEPSP + S3P + glyphosate<br />
+
 +
**[[1g6p]] - EcEPSP + S3P + glyphosate<br />
 +
**[[2qft]], [[2qfu]], [[3fjz]], [[3fk1]] - EcEPSP (mutant) + S3P + glyphosate<br />
 +
**[[2aay]] - EcEPSP + shikimate + glyphosate<br />
 +
**[[1rf6]] - SpEPSP + S3P + glyphosate<br />
 +
**[[2gga]] - AgEPSP + S3P + glyphosate<br />
 +
**[[4ggd]] - AgEPSP (mutant) + S3P + glyphosate<br />
 +
**[[2o0e]] - MtEPSP + S3P + phosphoenolpyruvate<br />
 +
**[[3nvs]] - VcEPSP + S3P + glyphosate <br />
 +
**[[3slh]] - CbEPSP + S3P + glyphosate<br />
 +
}}
- 
- 
- 
- 
- 
-
</StructureSection>
 
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:44, 24 November 2014

Structure of EPSP Synthase

Structure of EPSP synthase (PDB entry 1eps)

Drag the structure with the mouse to rotate

3D structures of EPSP synthase

Updated on 24-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Ann Taylor, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/EPSP_synthase"
Personal tools