Galactosidase

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===α-Galactosidase===
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*α-Galactosidase
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[[3lrk]] – yAgal 1 (mutant) – yeast<br />
+
**[[3lrk]] – yAgal 1 (mutant) – yeast<br />
-
[[3lrl]], [[3lrm]] – yAgal 1 (mutant) + polysaccharide<br />
+
**[[3lrl]], [[3lrm]] – yAgal 1 (mutant) + polysaccharide<br />
-
[[3lx9]], [[3lxa]], [[3lxb]], [[3lxc]], [[3tv8]] - hAgal A (mutant) – human<br />
+
**[[3lx9]], [[3lxa]], [[3lxb]], [[3lxc]], [[3tv8]] - hAgal A (mutant) – human<br />
-
[[3hg2]], [[3gxn]], [[1r46]], [[1r47]], [[3s5y]], [[3s5z]] – hAgal A<br />
+
**[[3hg2]], [[3gxn]], [[1r46]], [[1r47]], [[3s5y]], [[3s5z]] – hAgal A<br />
For [[3hg2]] <scene name='3hg2/3hg2to3morph/6'>click here to see cycling morph from empty active site to substrate bound form and back</scene>.<br />
For [[3hg2]] <scene name='3hg2/3hg2to3morph/6'>click here to see cycling morph from empty active site to substrate bound form and back</scene>.<br />
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[[1zy9]] – TmAgal – ''Thermotoga maritima''<br />
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**[[1zy9]] – TmAgal – ''Thermotoga maritima''<br />
-
[[3h53]] - hAgal B (mutant)<br />
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**[[3h53]] - hAgal B (mutant)<br />
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[[3a24]] – BtAgal – ''Bacterioides thetaiotamicron''<br />
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**[[3a24]] – BtAgal – ''Bacterioides thetaiotamicron''<br />
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[[3a5v]] – Agal I – ''Mortierella vinacea''<br />
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**[[3a5v]] – Agal I – ''Mortierella vinacea''<br />
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[[3mi6]] – Agal – ''Lactobacillus brevis''<br />
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**[[3mi6]] – Agal – ''Lactobacillus brevis''<br />
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[[1szn]] – HjAgal – ''Hypocrea jecorina''<br />
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**[[1szn]] – HjAgal – ''Hypocrea jecorina''<br />
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[[1uas]] – Agal – rice<br />
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**[[1uas]] – Agal – rice<br />
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[[2xn0]], [[2xn1]] – LaAgal – ''Lactobacillus acidophilus''<br />
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**[[2xn0]], [[2xn1]] – LaAgal – ''Lactobacillus acidophilus''<br />
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[[4fnp]] – GsAgal (mutant) – ''Geobacillus stearothermophilus''<br />
+
**[[4fnp]] – GsAgal (mutant) – ''Geobacillus stearothermophilus''<br />
-
[[4fnq]], [[4fnr]] – GsAgal
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**[[4fnq]], [[4fnr]] – GsAgal
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''α-galactosidase binary complex''
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*''α-galactosidase binary complex''
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[[3h54]] - hAgal B (mutant) + polysaccharide<br />
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**[[3h54]] - hAgal B (mutant) + polysaccharide<br />
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[[3h55]] - hAgal B (mutant) + galactose<br />
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**[[3h55]] - hAgal B (mutant) + galactose<br />
-
[[3igu]] - hAgal B (mutant) + intermediate<br />
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**[[3igu]] - hAgal B (mutant) + intermediate<br />
-
[[3hg3]], [[3hg5]] - hAgal A (mutant) + galactose<br />
+
**[[3hg3]], [[3hg5]] - hAgal A (mutant) + galactose<br />
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[[3gxp]] - hAgal A + galactose<br />
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**[[3gxp]] - hAgal A + galactose<br />
-
[[3hg4]] – hAgal A + intermediate<br />
+
**[[3hg4]] – hAgal A + intermediate<br />
-
[[3gxt]] – hAgal A + imino sugar<br />
+
**[[3gxt]] – hAgal A + imino sugar<br />
-
[[1t0o]] – HjAgal + galactose<br />
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**[[1t0o]] – HjAgal + galactose<br />
-
[[2xn2]] - LaAgal + galactose<br />
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**[[2xn2]] - LaAgal + galactose<br />
-
[[4fns]] - GsAgal (mutant) + jirimycin derivative<br />
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**[[4fns]] - GsAgal (mutant) + jirimycin derivative<br />
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[[4fnt]], [[4fnu]] – GsAgal + galactoside
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**[[4fnt]], [[4fnu]] – GsAgal + galactoside
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===β-Galactosidase===
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*β-Galactosidase
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[[3og2]] – TrBgal – ''Trichoderma reesei''<br />
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**[[3og2]] – TrBgal – ''Trichoderma reesei''<br />
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[[3muy]], [[3i3e]], [[3iap]], [[3iaq]], [[3dyp]], [[1px3]], [[3sep]], [[3t0a]], [[3t2o]], [[3vd3]], [[3vd5]], [[3vda]], [[4duv]] – EcBgal (mutant) – ''Escherichia coli''<br />
+
**[[3muy]], [[3i3e]], [[3iap]], [[3iaq]], [[3dyp]], [[1px3]], [[3sep]], [[3t0a]], [[3t2o]], [[3vd3]], [[3vd5]], [[3vda]], [[4duv]] – EcBgal (mutant) – ''Escherichia coli''<br />
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[[1hn1]], [[1dp0]], [[1f49]], [[1f4a]], [[1f4h]], [[1gho]], [[1bgl]], [[1bgm]] - EcBgal<br />
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**[[1hn1]], [[1dp0]], [[1f49]], [[1f4a]], [[1f4h]], [[1gho]], [[1bgl]], [[1bgm]] - EcBgal<br />
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[[3dec]], [[3d3a]], [[3bga]] – BtBgal<br />
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**[[3dec]], [[3d3a]], [[3bga]] – BtBgal<br />
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[[1yq2]] - Bgal (mutant) – Arthrobacter<br />
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**[[1yq2]] - Bgal (mutant) – Arthrobacter<br />
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[[1uwi]], [[4eam]] - SsBgal (mutant) - ''Sulfolobus solfataricus''<br />
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**[[1uwi]], [[4eam]] - SsBgal (mutant) - ''Sulfolobus solfataricus''<br />
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[[1uwq]], [[4gow]] – SsBgal<br />
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**[[1uwq]], [[4gow]] – SsBgal<br />
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[[1kwg]] – TtBgal – ''Thermus thermophilus''<br />
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**[[1kwg]] – TtBgal – ''Thermus thermophilus''<br />
-
[[1tg7]] – PeBgal – ''Penicillium''<br />
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**[[1tg7]] – PeBgal – ''Penicillium''<br />
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[[3tts]] – BcBgal – ''Bacillus circulans''<br />
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**[[3tts]] – BcBgal – ''Bacillus circulans''<br />
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[[4ha3]], [[4ha4]] – Bgal – ''Acidilobus saccharovorans''<br />
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**[[4ha3]], [[4ha4]] – Bgal – ''Acidilobus saccharovorans''<br />
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[[3w5f]] – toBgal – tomato<br />
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**[[3w5f]] – toBgal – tomato<br />
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''β-Galactosidase binary complex''
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*''β-Galactosidase binary complex''
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[[1xc6]] - PeBgal + galactose<br />
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**[[1xc6]] - PeBgal + galactose<br />
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[[3w5g]] - toBgal + galactose<br />
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**[[3w5g]] - toBgal + galactose<br />
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[[1kwk]] – TtBgal + galactose<br />
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**[[1kwk]] – TtBgal + galactose<br />
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[[3ogr]] – TrBgal + galactose<br />
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**[[3ogr]] – TrBgal + galactose<br />
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[[3ogs]] - TrBgal + IPTG<br />
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**[[3ogs]] - TrBgal + IPTG<br />
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[[3ogv]] – TrBgal + inhibitor<br />
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**[[3ogv]] – TrBgal + inhibitor<br />
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[[2ceq]], [[1uwr]], [[1uws]], [[1uwt]], [[1uwu]], [[2cer]] - SsBgal + inhibitor<br />
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**[[2ceq]], [[1uwr]], [[1uws]], [[1uwt]], [[1uwu]], [[2cer]] - SsBgal + inhibitor<br />
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[[4ean]] – SsBgal + indole<br />
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**[[4ean]] – SsBgal + indole<br />
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[[3muz]], [[3i3d]], [[3dyo]], [[1px4]], [[1jyx]], [[3t08]], [[3t0b]], [[3t2p]], [[3vd4]], [[3vd9]], [[3vdc]]- EcBgal (mutant) + IPTG<br />
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**[[3muz]], [[3i3d]], [[3dyo]], [[1px4]], [[1jyx]], [[3t08]], [[3t0b]], [[3t2p]], [[3vd4]], [[3vd9]], [[3vdc]]- EcBgal (mutant) + IPTG<br />
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[[3mv0]], [[3i3b]], [[3czj]], [[1jz0]], [[1jz1]], [[1jz2]], [[1jz3]], [[1jz4]], [[1jz5]], [[1jz6]] - EcBgal (mutant) + intermediate<br />
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**[[3mv0]], [[3i3b]], [[3czj]], [[1jz0]], [[1jz1]], [[1jz2]], [[1jz3]], [[1jz4]], [[1jz5]], [[1jz6]] - EcBgal (mutant) + intermediate<br />
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[[3mv1]] - EcBgal (mutant) + guanidinium<br />
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**[[3mv1]] - EcBgal (mutant) + guanidinium<br />
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[[3e1f]], [[1jz7]] - EcBgal (mutant) + galactose<br />
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**[[3e1f]], [[1jz7]] - EcBgal (mutant) + galactose<br />
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[[3t09]], [[3t0d]], [[3t2q]], [[3vd7]], [[3vdb]] - EcBgal (mutant) + galactose derivative<br />
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**[[3t09]], [[3t0d]], [[3t2q]], [[3vd7]], [[3vdb]] - EcBgal (mutant) + galactose derivative<br />
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[[1jyn]], [[1jyy]], [[1jyz]], [[1jz8]] - EcBgal (mutant) + lactose derivative<br />
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**[[1jyn]], [[1jyy]], [[1jyz]], [[1jz8]] - EcBgal (mutant) + lactose derivative<br />
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[[1jyn]], [[1jyw]], [[1jyv]] - EcBgal (mutant) + substrate<br />
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**[[1jyn]], [[1jyw]], [[1jyv]] - EcBgal (mutant) + substrate<br />
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[[1jz6]] - EcBgal (mutant) + inhibitor<br />
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**[[1jz6]] - EcBgal (mutant) + inhibitor<br />
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[[4duw]] - EcBgal (mutant) + allolactose<br />
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**[[4duw]] - EcBgal (mutant) + allolactose<br />
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[[4dux]] - EcBgal (mutant) + ribose<br />
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**[[4dux]] - EcBgal (mutant) + ribose<br />
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[[4ckd]] – EcBgal + antibody<br />
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**[[4ckd]] – EcBgal + antibody<br />
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[[4iug]] - Bgal + galactose – ''Aspergillus oryzae''<br />
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**[[4iug]] - Bgal + galactose – ''Aspergillus oryzae''<br />
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[[3ob8]], [[3oba]] – Bgal – ''Kluyveromyces lactis''<br />
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**[[3ob8]], [[3oba]] – Bgal – ''Kluyveromyces lactis''<br />
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[[3tty]] - BcBgal + galactose<br />
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**[[3tty]] - BcBgal + galactose<br />
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[[3thd]] – hBgal + jirimycin derivative<br />
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**[[3thd]] – hBgal + jirimycin derivative<br />
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[[3thc]] - hBgal + galactose<br />
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**[[3thc]] - hBgal + galactose<br />
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===Endo-1,4-β-galactosidase===
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*Endo-1,4-β-galactosidase
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[[2xom]], [[2xon]] – TmEbgal carbohydrate-binding domain + β-galactotriose<br />
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**[[2xom]], [[2xon]] – TmEbgal carbohydrate-binding domain + β-galactotriose<br />
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[[1ups]] – Ebgal - ''Clostridium perfringens''<br />
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**[[1ups]] – Ebgal - ''Clostridium perfringens''<br />
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[[2ygl]], [[2ygm]] – Ebgal blood group A & B cleaving – ''Streptococcus pneumoniae''<br />
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**[[2ygl]], [[2ygm]] – Ebgal blood group A & B cleaving – ''Streptococcus pneumoniae''<br />
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[[4bg7]] – Ebgal – ''Emericella nidulans''<br />
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**[[4bg7]] – Ebgal – ''Emericella nidulans''<br />
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===3,6-anhydro-α-L-galactosidase===
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*3,6-anhydro-α-L-galactosidase
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[[3p2n]] – AAgal – ''Zobellia galactanivorans''<br />
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**[[3p2n]] – AAgal – ''Zobellia galactanivorans''<br />
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[[4ak5]] – BpAAgal – ''Bacterioides plebeius''<br />
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**[[4ak5]] – BpAAgal – ''Bacterioides plebeius''<br />
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[[4ak6]] – BpAAgal (mutant)<br />
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**[[4ak6]] – BpAAgal (mutant)<br />
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[[4ak7]] – BpAAgal (mutant) + polysaccharide<br />
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**[[4ak7]] – BpAAgal (mutant) + polysaccharide<br />
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===6-phospho-β-D-galactosidase===
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*6-phospho-β-D-galactosidase
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+
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[[2pbg]], [[3pbg]], [[4pbg]], [[1pbg]] – Pgal (mutant) – ''Lactococcus lacti''<br />
+
-
[[2v4v]] – gal GH59 – ''Clostridium cellulolyticum''
+
 +
**[[2pbg]], [[3pbg]], [[4pbg]], [[1pbg]] – Pgal (mutant) – ''Lactococcus lacti''<br />
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**[[2v4v]] – gal GH59 – ''Clostridium cellulolyticum''
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]
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*Created with the participation of [[User:Wayne Decatur|Wayne Decatur]].
*Created with the participation of [[User:Wayne Decatur|Wayne Decatur]].

Revision as of 07:00, 26 November 2014

Template:STRUCTURE 3e1f

α-Galactosidase (Agal) hydrolyzes the terminal α-galactosyl moiety from glycoproteins and glycolipids. β-Galactosidase (Bgal) hydrolyzes β-galactosides into monosaccharides. Isopropyl-β-d-thiogalactopyranoside (IPTG) induces Bgal activity. Phenylethyl-β-d-thiogalactopyranoside (PETG) is an inhibitor. Galactose, lactose, o-nitrophenyl-β-d-galactoside (ONPG) are substrates. Galactopyranosyl is reaction intermediate. The image at the right correspond to one representative galactosidase, i.e. the crystal structure of galactosidase from Escherichia coli (3e1f). For details on β-galactosidase see Molecular Playground/Beta-galactosidase.

3D Structures of Galactosidase

Updated on 26-November-2014

For 3hg2 .


Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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