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Methylesterase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===CheB methylesterase===
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*CheB methylesterase
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[[1chd]], [[1a2o]] – ME – ''Salmonella typhimurium''<br />
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**[[1chd]], [[1a2o]] – ME – ''Salmonella typhimurium''<br />
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[[3sft]] – TmME catalytic domain – ''Thermotoga maritima''<br />
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**[[3sft]] – TmME catalytic domain – ''Thermotoga maritima''<br />
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[[3t8y]] – TmME response regulator domain
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**[[3t8y]] – TmME response regulator domain
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===Pectin methylesterase===
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*Pectin methylesterase
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[[1qjv]] – EcME – ''Erwinia chrysanthemi''<br />
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**[[1qjv]] – EcME – ''Erwinia chrysanthemi''<br />
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[[1gq8]] – ME – carrot<br />
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**[[1gq8]] – ME – carrot<br />
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[[3uw0]] – ME – ''Yersinia enterocolitica''<br />
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**[[3uw0]] – ME – ''Yersinia enterocolitica''<br />
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[[1xg2]] – ME + protein inhibitor – ''Solanum lycopersicum''<br />
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**[[1xg2]] – ME + protein inhibitor – ''Solanum lycopersicum''<br />
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[[2nsp]], [[2nst]], [[2nt6]], [[2nt9]] – EcME (mutant) + hexasaccharide<br />
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**[[2nsp]], [[2nst]], [[2nt6]], [[2nt9]] – EcME (mutant) + hexasaccharide<br />
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[[2ntp]], [[2ntb]], [[2ntq]] – EcME + hexasaccharide
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**[[2ntp]], [[2ntb]], [[2ntq]] – EcME + hexasaccharide
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===Aclacinomycin methylesterase===
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*Aclacinomycin methylesterase
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[[1q0r]], [[1q0z]] – ME + product analog – ''Streptomyces purpurascens''
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**[[1q0r]], [[1q0z]] – ME + product analog – ''Streptomyces purpurascens''
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===Protein phosphatase methylesterase===
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*Protein phosphatase methylesterase
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[[3c5v]] – hME1 – human<br />
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**[[3c5v]] – hME1 – human<br />
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[[3c5w]] – hME1 + protein phosphatase 2A
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**[[3c5w]] – hME1 + protein phosphatase 2A
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===4-o-methyl-glucuronoyl methylesterase===
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*4-o-methyl-glucuronoyl methylesterase
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[[4g4g]] – MtME – ''Myceliophthora thermophila''<br />
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[[4g4i]] – MtME (mutant)<br />
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[[4g4j]] – MtME (mutant) + 4-o-methyl-β-D-glucopyranuronate<br />
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**[[4g4g]] – MtME – ''Myceliophthora thermophila''<br />
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**[[4g4i]] – MtME (mutant)<br />
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**[[4g4j]] – MtME (mutant) + 4-o-methyl-β-D-glucopyranuronate<br />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:29, 1 December 2014

Template:STRUCTURE 3uw0 Methylesterase (ME) removes a methyl group from the Υ-glutamyl methyl esther residues of methyl-accepting chemotaxis proteins. ME participates in several metabolic pathways. Protein phosphatase ME is involved in the reversible methylation of protein phosphatase 2A which is active in cellular regulation.

  • CheB ME is a phosphorylation-activated response regulator involved in reversible modification of bacterial chemotaxis receptors.
  • Pectin ME causes demethylation of cell wall polygalactorunanas. It is involved in pectin digestion. The reaction products liberate frothing agents causing bloating in cattle.
  • Aclacinomycin ME modifies the aklavinone skeleton in the biosynthesis of anthracyclins in Streptomyces species.
  • Protein phosphatase ME is a key regulator of protein phosphatase 2A.
  • 4-o-methyl-glucuronoyl ME has a significant role in biomass degradation.

3D structures of methylesterase

Updated on 01-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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