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Neurexin

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{{STRUCTURE_3bod| PDB=3bod | SIZE=400| SCENE= |right|CAPTION=Mouse neurexin 1α LNS domain with Ca+2 ion ([[3bod]]) }}
{{STRUCTURE_3bod| PDB=3bod | SIZE=400| SCENE= |right|CAPTION=Mouse neurexin 1α LNS domain with Ca+2 ion ([[3bod]]) }}
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== 3D Structures of Neurexin ==
== 3D Structures of Neurexin ==
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''Updated February 2013''
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{{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===NRXN===
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[[3mw2]] – mNRXN-1α LNS domain+splice insert 4 – mouse<br />
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*Neurexin
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[[3bod]], [[3bop]] - mNRXN-1α LNS domain<br />
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[[3mw3]], [[2r1b]] - rNRXN-1α LNS domain+splice insert 4 – rat<br />
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[[2r16]] - rNRXN-1α LNS domain+Ca<br />
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[[1c4r]] - rNRXN-1α LNS domain<br />
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[[3mw4]] - mNRXN-1α LNS domain<br />
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[[2h0b]] - bNRXN-1α LNS2 domain – bovine<br />
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[[3asi]] - bNRXN-1α LNS5-EGF3-LNS6 domains<br />
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[[3poy]] - bNRXN-1α LNS2-LNS6 domains (mutant)<br />
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[[3qcw]], [[3r05]] - bNRXN-1α LNS1-LNS6 domains (mutant)<br />
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[[2r1d]] - rNRXN-1β LNS/LG domain
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===NRXN+NLGN===
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**[[3mw2]] – mNRXN-1α LNS domain+splice insert 4 – mouse<br />
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**[[3bod]], [[3bop]] - mNRXN-1α LNS domain<br />
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**[[3mw3]], [[2r1b]] - rNRXN-1α LNS domain+splice insert 4 – rat<br />
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**[[2r16]] - rNRXN-1α LNS domain+Ca<br />
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**[[1c4r]] - rNRXN-1α LNS domain<br />
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**[[3mw4]] - mNRXN-1α LNS domain<br />
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**[[2h0b]] - bNRXN-1α LNS2 domain – bovine<br />
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**[[3asi]] - bNRXN-1α LNS5-EGF3-LNS6 domains<br />
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**[[3poy]] - bNRXN-1α LNS2-LNS6 domains (mutant)<br />
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**[[3qcw]], [[3r05]] - bNRXN-1α LNS1-LNS6 domains (mutant)<br />
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**[[2r1d]] - rNRXN-1β LNS/LG domain
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[[2xb6]], [[2wqz]] – rNRXN-1α LNS domain +hNLGN-4 cholinesterase domain<br />
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*NRXN+Neuroligin
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[[3b3q]] - hNRXN-1α LNS domain+mNLGN-4 cholinesterase domain<br />
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[[3biw]] - rNRXN-1α LNS domain+rNLGN-1 cholinesterase domain<br />
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[[3vkf]] - bNRXN-1β LNS domain+rNLGN-1 cholinesterase domain
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**[[2xb6]], [[2wqz]] – rNRXN-1α LNS domain +hNLGN-4 cholinesterase domain<br />
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**[[3b3q]] - hNRXN-1α LNS domain+mNLGN-4 cholinesterase domain<br />
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**[[3biw]] - rNRXN-1α LNS domain+rNLGN-1 cholinesterase domain<br />
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**[[3vkf]] - bNRXN-1β LNS domain+rNLGN-1 cholinesterase domain
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:34, 1 December 2014

Template:STRUCTURE 3bod

Neurexins (NRXN) are a family of presynaptic proteins which bind to the postsynaptic Neuroligin (NLGN) to form a complex which attaches neurons. The NRXN family contains 4 members which are numbered 1 to 4. The NRXN-α contains 6 homologous LNS domains while the NRXN-β contains only LNS6. See Neurodevelopmental Disorders.

For Structural Analysis of Neurexin, See: Neuroligin-Neurexin Interaction

3D Structures of Neurexin

01-December-2014

Retrieved from "http://52.214.119.220/wiki/index.php/Neurexin"
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