Neuropilin

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===NRP-1===
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*NRP-1
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[[1kex]], [[2qqi]] – hNRP-1 B domain – human
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**[[1kex]], [[2qqi]] – hNRP-1 B domain – human
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[[2qqm]] - hNRP-1 A+B domain<br />
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**[[2qqm]] - hNRP-1 A+B domain<br />
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[[4deq]] - hNRP-1 B domain + VEGF-A heparin-binding domain<br />
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**[[4deq]] - hNRP-1 B domain + VEGF-A heparin-binding domain<br />
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[[2qqn]] - hNRP-1 B domain + VEGF-blocking antibody
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**[[2qqn]] - hNRP-1 B domain + VEGF-blocking antibody
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[[3i97]] - hNRP-1 B domains + inhibitor
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**[[3i97]] - hNRP-1 B domains + inhibitor
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[[2orx]] – rNRP-1 C1+C2 domains – rat
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**[[2orx]] – rNRP-1 C1+C2 domains – rat
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[[2orz]] – rNRP-1 + tuftsin peptide<br />
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**[[2orz]] – rNRP-1 + tuftsin peptide<br />
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[[4gz9]] - mNRP-1 A+B domain – mouse<br />
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**[[4gz9]] - mNRP-1 A+B domain – mouse<br />
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[[4gza]] - mNRP-1 A+B domain + plexin A2 + semaphorin 3A
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**[[4gza]] - mNRP-1 A+B domain + plexin A2 + semaphorin 3A
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===NRP-2===
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*NRP-2
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[[2qqj]] - hNRP-2 B domain
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**[[2qqj]] - hNRP-2 B domain
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[[2qqo]] - hNRP-2 A+B domains
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**[[2qqo]] - hNRP-2 A+B domains
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[[2qqk]], [[2qql]] - hNRP-2 A+B domains + semaphorin-blocking antibody
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**[[2qqk]], [[2qql]] - hNRP-2 A+B domains + semaphorin-blocking antibody
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[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:38, 1 December 2014

Template:STRUCTURE 2qqm

Neuropilin (NRP) are neuronal receptors. NRP are co-receptors for semaphorins. There are 2 classes of NRP – NRP-1 and NRP-2.

  • NRP-1 has high affinity for semaphorin-3A.
  • NRP-2 has high affinity for semaphorin-3F.

Contents

3D Structures of Neuropilin

Updated on 01-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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