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3fwa

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[[Image:3fwa.png|left|200px]]
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==Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline==
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<StructureSection load='3fwa' size='340' side='right' caption='[[3fwa]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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{{STRUCTURE_3fwa| PDB=3fwa | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3fwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FWA FirstGlance]. <br>
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===Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=REN:(S)-RETICULINE'>REN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3d3d|3d3d]], [[3d2h|3d2h]], [[3d2j|3d2j]], [[3fw7|3fw7]], [[3fw8|3fw8]], [[3fw9|3fw9]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BBE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3467 Eschscholzia californica])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Reticuline_oxidase Reticuline oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.21.3.3 1.21.3.3] </span></td></tr>
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[[3fwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [http://www.ebi.ac.uk/pdbsum/3fwa PDBsum]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/3fwa_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Eschscholzia californica]]
[[Category: Eschscholzia californica]]
[[Category: Reticuline oxidase]]
[[Category: Reticuline oxidase]]
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[[Category: Gruber, K.]]
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[[Category: Gruber, K]]
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[[Category: Macheroux, P.]]
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[[Category: Macheroux, P]]
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[[Category: Winkler, A.]]
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[[Category: Winkler, A]]
[[Category: Alakloid biosynthesis]]
[[Category: Alakloid biosynthesis]]
[[Category: Alkaloid metabolism]]
[[Category: Alkaloid metabolism]]

Revision as of 10:24, 3 December 2014

Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline

3fwa, resolution 1.50Å

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