1n45

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[[Image:1n45.gif|left|200px]]<br /><applet load="1n45" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1n45.gif|left|200px]]
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caption="1n45, resolution 1.50&Aring;" />
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'''X-RAY CRYSTAL STRUCTURE OF HUMAN HEME OXYGENASE-1 (HO-1) IN COMPLEX WITH ITS SUBSTRATE HEME'''<br />
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{{Structure
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|PDB= 1n45 |SIZE=350|CAPTION= <scene name='initialview01'>1n45</scene>, resolution 1.50&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Heme_oxygenase Heme oxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.3 1.14.99.3]
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|GENE= HMOX1, HO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''X-RAY CRYSTAL STRUCTURE OF HUMAN HEME OXYGENASE-1 (HO-1) IN COMPLEX WITH ITS SUBSTRATE HEME'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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1N45 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 1QQ8. Active as [http://en.wikipedia.org/wiki/Heme_oxygenase Heme oxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.3 1.14.99.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N45 OCA].
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1N45 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 1QQ8. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N45 OCA].
[[Category: Heme oxygenase]]
[[Category: Heme oxygenase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: HEM]]
[[Category: HEM]]
[[Category: SO4]]
[[Category: SO4]]
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[[Category: alpha helices]]
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[[Category: alpha helice]]
[[Category: heme-binding site]]
[[Category: heme-binding site]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:02:02 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:51:53 2008''

Revision as of 10:51, 20 March 2008


PDB ID 1n45

Drag the structure with the mouse to rotate
, resolution 1.50Å
Ligands: and
Gene: HMOX1, HO1 (Homo sapiens)
Activity: Heme oxygenase, with EC number 1.14.99.3
Coordinates: save as pdb, mmCIF, xml



X-RAY CRYSTAL STRUCTURE OF HUMAN HEME OXYGENASE-1 (HO-1) IN COMPLEX WITH ITS SUBSTRATE HEME


Disease

Known diseases associated with this structure: Epiphyseal dysplasia, multiple, 5 OMIM:[602109], Heme oxygenase-1 deficiency OMIM:[141250], Osteoarthritis, hand, susceptibility to OMIM:[602109], Spondyloepimetaphyseal dysplasia OMIM:[602109]

About this Structure

1N45 is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1QQ8. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 12:51:53 2008

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