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1n56

From Proteopedia

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[[Image:1n56.gif|left|200px]]<br /><applet load="1n56" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1n56.gif|left|200px]]
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caption="1n56, resolution 2.4&Aring;" />
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'''Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion'''<br />
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{{Structure
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|PDB= 1n56 |SIZE=350|CAPTION= <scene name='initialview01'>1n56</scene>, resolution 2.4&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=ATP:ADENOSINE-5'-TRIPHOSPHATE'>ATP</scene>
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|ACTIVITY=
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|GENE= dpo4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])
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}}
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'''Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1N56 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=ATP:'>ATP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N56 OCA].
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1N56 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N56 OCA].
==Reference==
==Reference==
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Error-prone DNA polymerases: novel structures and the benefits of infidelity., Friedberg EC, Fischhaber PL, Kisker C, Cell. 2001 Oct 5;107(1):9-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11595180 11595180]
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Error-prone DNA polymerases: novel structures and the benefits of infidelity., Friedberg EC, Fischhaber PL, Kisker C, Cell. 2001 Oct 5;107(1):9-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11595180 11595180]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Sulfolobus solfataricus]]
[[Category: Sulfolobus solfataricus]]
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[[Category: y-family]]
[[Category: y-family]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:02:24 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:52:17 2008''

Revision as of 10:52, 20 March 2008

Image:1n56.gif


PDB ID 1n56

Drag the structure with the mouse to rotate
, resolution 2.4Å
Ligands: , and
Gene: dpo4 (Sulfolobus solfataricus)
Coordinates: save as pdb, mmCIF, xml



Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion


Overview

Studies on several recently discovered error-prone DNA polymerases reveal novel structures that may explain the low fidelity of this general class of enzymes, a number of which are involved in the replicative bypass (translesion synthesis) of base damage in DNA.

About this Structure

1N56 is a Single protein structure of sequence from Sulfolobus solfataricus. Full crystallographic information is available from OCA.

Reference

Error-prone DNA polymerases: novel structures and the benefits of infidelity., Friedberg EC, Fischhaber PL, Kisker C, Cell. 2001 Oct 5;107(1):9-12. PMID:11595180

Page seeded by OCA on Thu Mar 20 12:52:17 2008

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